Reducing antibiotic use in nursing home residents with dementia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pragmatic cluster randomized clinical trial aims to improve the management of suspected infections in nursing home residents with dementia. It will compare a multicomponent intervention designed to optimize infection management against usual care in a population of 600 residents across 50 nursing homes. The study will assess the impact of the intervention on antibiotic use and the number of burdensome procedures over a 24-month period. Data will be collected from electronic health records and analyzed to determine the effectiveness of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age \> 60
2. A diagnosis of dementia (any type)
3. Cognitive Functional Scale (CFS) \> 1
4. NH length of stay \>90 days

The CFS score categorizes cognitive impairment status based on data in the electronic health record into: 1. None, 2. Mild, 3. Moderate, and 4. Severe (advanced). For the primary outcome, the analysis will be restricted to residents with a CFS score of 3 or 4.

Exclusion Criteria:

1. Less than 60 years of age
2. Living in nursing home for less than 90 days
3. Does not have diagnosis of dementia
4. Does not meet CFS \>1 score

Where it's running

• Hebrew SeniorLife
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Susan Mitchell, MD, MPH — Hebrew SeniorLife
• Study coordinator: Susan Mitchell, MD, MPH
• Email: smitchell@hsl.harvard.edu
• Phone: 16172813669

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.