Red Ultraviolet Hair Imaging and Hair Growth in Alopecia Areata
Official title: Evaluation of UV-Trichoscopic Red Fluorescence Intensity in Relation to Trichoscopic Findings and Response to Intralesional Corticosteroid Treatment in Limited Plaque-Type Alopecia Areata
Run by Istanbul Training and Research Hospital · NCT07803874 · Data updated 2026-11-12
This observational study checks if red fluorescence seen with UV hair imaging relates to disease features and how well hair regrows after standard intralesional corticosteroid treatment in adults with limited plaque-type alopecia areata.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Istanbul Training and Research Hospital Government |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT07803874 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with limited plaque-type alopecia areata of the scalp who are scheduled to receive intralesional corticosteroid treatment as part of their standard care.
✕Probably not a fit
Patients who do not show a correlation between red fluorescence and hair regrowth, or who do not receive meaningful regrowth, may not derive a predictive benefit from the imaging approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational cohort study follows adults with limited plaque-type alopecia areata who are receiving intralesional corticosteroid injections as part of their usual care. Participants undergo baseline polarized trichoscopy and UV-trichoscopy, with follow-up imaging at weeks 4, 8, and 12 to track hair regrowth and changes in scalp findings. Red fluorescence intensity on standardized images is measured and analyzed for associations with treatment response and baseline trichoscopic features. The study does not alter treatment decisions; it only observes imaging biomarkers and their potential relationship to clinical outcomes. Imaging and analysis use standardized protocols to enable comparability across visits.
Why it matters
Potential benefit: If red fluorescence reliably predicts treatment response, clinicians could use UV-trichoscopy to tailor therapy for alopecia areata.
How similar studies have gone: Previous work has explored trichoscopy markers in alopecia areata, but this specific UV-red fluorescence correlation with treatment response is relatively novel and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Limited plaque-type alopecia areata of the scalp * Active hair loss * Symptom onset within the previous 6 months * No topical, intramuscular, or oral treatment for alopecia areata within the previous 1 month * No intralesional corticosteroid treatment within the previous 6 weeks * Provision of informed consent Exclusion Criteria: * Beard alopecia areata * Very extensive alopecia areata or multiple large plaques * Tinea capitis or active infection * Current phototherapy * Systemic immunosuppressive treatment within the washout period specified in the study protocol * Pregnancy or breastfeeding * Contraindication to UV imaging
Where it's running
-
Istanbul Training and Research Hospital
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Sevgi Nazli Apucu, Dermatology Resident Physician
- Email: snapucu@gmail.com
- Phone: +905374048180
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.