Clinical trial Recruiting at 1 site Observational Ages 18 and up

Red Ultraviolet Hair Imaging and Hair Growth in Alopecia Areata

Official title: Evaluation of UV-Trichoscopic Red Fluorescence Intensity in Relation to Trichoscopic Findings and Response to Intralesional Corticosteroid Treatment in Limited Plaque-Type Alopecia Areata

Run by Istanbul Training and Research Hospital · NCT07803874 · Data updated 2026-11-12

This observational study checks if red fluorescence seen with UV hair imaging relates to disease features and how well hair regrows after standard intralesional corticosteroid treatment in adults with limited plaque-type alopecia areata.

More Alopecia Areata trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment40 (estimated)
SponsorIstanbul Training and Research Hospital
Government
Locations1 site (Istanbul)
StatusRecruiting
StartedJuly 1, 2026
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedSeptember 11, 2026
Trial IDNCT07803874 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with limited plaque-type alopecia areata of the scalp who are scheduled to receive intralesional corticosteroid treatment as part of their standard care.

Probably not a fit

Patients who do not show a correlation between red fluorescence and hair regrowth, or who do not receive meaningful regrowth, may not derive a predictive benefit from the imaging approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational cohort study follows adults with limited plaque-type alopecia areata who are receiving intralesional corticosteroid injections as part of their usual care. Participants undergo baseline polarized trichoscopy and UV-trichoscopy, with follow-up imaging at weeks 4, 8, and 12 to track hair regrowth and changes in scalp findings. Red fluorescence intensity on standardized images is measured and analyzed for associations with treatment response and baseline trichoscopic features. The study does not alter treatment decisions; it only observes imaging biomarkers and their potential relationship to clinical outcomes. Imaging and analysis use standardized protocols to enable comparability across visits.

Why it matters

Potential benefit: If red fluorescence reliably predicts treatment response, clinicians could use UV-trichoscopy to tailor therapy for alopecia areata.

How similar studies have gone: Previous work has explored trichoscopy markers in alopecia areata, but this specific UV-red fluorescence correlation with treatment response is relatively novel and exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Limited plaque-type alopecia areata of the scalp
* Active hair loss
* Symptom onset within the previous 6 months
* No topical, intramuscular, or oral treatment for alopecia areata within the previous 1 month
* No intralesional corticosteroid treatment within the previous 6 weeks
* Provision of informed consent

Exclusion Criteria:

* Beard alopecia areata
* Very extensive alopecia areata or multiple large plaques
* Tinea capitis or active infection
* Current phototherapy
* Systemic immunosuppressive treatment within the washout period specified in the study protocol
* Pregnancy or breastfeeding
* Contraindication to UV imaging

Where it's running

  • Istanbul Training and Research Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.