Reconstruction of oral cavity and oropharyngeal defects using reinnervated flaps

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the sensory recovery and functional outcomes in patients undergoing reconstruction of oral cavity and oropharyngeal defects using reinnervated profunda artery perforator (PAP) flaps. The research focuses on patients who have experienced significant functional deficits due to tumor resections, impacting their swallowing and speech abilities. By employing non-invasive testing methods, the study aims to assess the effectiveness of sensory recovery following the surgical intervention. The PAP flap is being explored as a viable alternative for patients with specific anatomical considerations, particularly those with thin lateral thigh thickness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Patient with defect involving the oral cavity or oropharynx who undergo reconstruction with a free reinnervated profunda artery perforator flap

Exclusion Criteria:

* \<18 years old
* Defect localizations other than the oral cavity or oropharynx
* Not able to give informed consent
* Inability to follow the procedures of the study, e.g., due to psychological disorders, dementia
* Inability or contraindications to undergo the investigated intervention

Where it's running

• University Hospital Basel
  Basel, Switzerland Recruiting

Study contacts

• Principal investigator: Nicole E. Speck, Dr. med. — University Hospital, Basel, Switzerland
• Study coordinator: Nicole E. Speck, Dr. med.
• Email: nicoleedith.speck@usb.ch
• Phone: +41 61 328 41 64

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.