Reconstruction of knee osteochondral defects with autologous cartilage or collagen matrix: clinical and MRI outcomes
Official title: Descriptive Study of the Reconstruction of Osteochondral Lesions of the Knee: Clinical and Imaging Results
Run by Versailles Hospital · NCT03908931 · Data updated 2026-11-12
This project will test whether autologous cartilage transplants or collagen knee matrices help adults with osteochondral knee defects and how the repair looks on MRI.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 130 (estimated) |
| Sponsor | Versailles Hospital Academic / other |
| Locations | 1 site (Le Chesnay) |
| Status | Recruiting |
| Started | April 1, 2019 |
| Main results expected | April 1, 2019 |
| Study ends | June 1, 2035 |
| Registry record updated | March 17, 2026 |
| Trial ID | NCT03908931 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with an osteochondral defect of the knee treated with autologous cartilage transplant or a collagen chondro-inducing knee matrix are ideal candidates.
✕Probably not a fit
Patients who had other cartilage repair techniques, who have lesions outside the knee, or who are under 18 are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults who have undergone cartilaginous reconstruction of the knee using either autologous cartilage transplant or a collagen chondro-inducing matrix will be followed for clinical outcomes and MRI imaging. Clinical scores and imaging findings will be collected to describe the quality of repair tissue and patient function. The study excludes other cartilage reconstruction techniques and lesions outside the knee. Results will be reported descriptively to fill gaps in the current literature on these specific reconstruction methods.
Why it matters
Potential benefit: If successful, the results could help doctors choose reconstruction methods that lead to better knee function and clearer MRI signs of repair.
How similar studies have gone: Similar cartilage transplant and collagen-matrix approaches have shown promising but variable clinical and imaging results, and robust comparative data remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * cartilaginous reconstruction by autologous transplant or collagenous chondro-inducing knee matrix * \> 18 years Exclusion Criteria: * Other cartilaginous reconstruction techniques, * other than knee joint
Where it's running
-
CH de Versailles
Le Chesnay, France Recruiting
Study contacts
- Study coordinator: Nicolas PUJOL
- Email: npujol@ch-versailles.fr
- Phone: +33139639565
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.