Reconstruction of deficient atrophic ridges using a guide bone regeneration technique
Reconstruction of Deficient Atrophic Ridges Using Guided Bone Regeneration Technique With Native Collagen Membrane and Polytetrafluoroethylene Membrane (Randomized Clinical Trial)
This study tests which type of membrane, either a synthetic or natural one, helps people with bone loss in their jaw grow more bone after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 20 Years to 48 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06746935 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of two different membrane types in ridge augmentation procedures for patients with deficient alveolar bone. Participants will be randomly assigned to receive either a Polytetrafluoroethylene membrane or a native collagen membrane after a mixture of autogenous and xenogenic bone is applied. Both groups will undergo diagnostic imaging and surgical procedures, with follow-up imaging conducted four months post-operation to assess outcomes. The study seeks to determine which membrane type yields better bone regeneration results.
Who should consider this trial
Good fit: Ideal candidates include patients with a maxillary residual alveolar bone height of at least 8 mm and width of 5 mm, who have at least one missing tooth and may have experienced previous implant or graft failures.
Not a fit: Patients who are heavy smokers, have bone diseases affecting healing, or uncontrolled metabolic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve bone regeneration techniques, leading to better outcomes for patients requiring dental implants.
How similar studies have performed: Other studies have shown promising results with similar approaches in bone augmentation, suggesting potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with maxillary residual alveolar bone height not less than 8 mm. * Alveolar bone width from less than or equal 5 mm. * Both sexes. * At least missing single tooth. * Previous Failed Implants. * Previous Failed Grafting. Exclusion Criteria: * Heavy smokers more than 20 cigarettes per day. * Patients with bone disease that may affect normal healing, example; hyperparathyroidism. * Patients had radiotherapy and chemotherapy in head and neck. * Patients had neoplasms in sites to be grafted. * Patients with Metabolic diseases uncontrolled diabetic patients, Glycated hemoglobin (Hb A1c) more than 7 mg\\dl.
Where this trial is running
Cairo
- Faculty of Dentistry Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohannad A. Ismail, MSc.
- Email: mohannadahmed@hotmail.com
- Phone: +201222968444
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.