Reconstruction of alveolar clefts using cortical-shell grafts

Evaluation of Secondary Alveolar Cleft Reconstruction With Labial and Palatal Retromolar Cortical-Shells (A Case Series Study)

Not applicable Interventional Beni-Suef University · NCT06585566

This study tests a new way to help kids with unilateral alveolar clefts by using a special bone graft to support their jaw and help their teeth grow properly.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment7 (estimated)
Ages8 Years to 15 Years
SexAll
SponsorBeni-Suef University Academic / other
Locations2 sites (Cairo and 1 other locations)
Trial IDNCT06585566 on ClinicalTrials.gov

What this trial studies

This study evaluates a technique for secondary alveolar bone grafting (SABG) aimed at rehabilitating the maxilla in patients with unilateral alveolar clefts. The approach utilizes a retromolar cortical shell graft to stabilize the maxillary foundation, facilitating tooth eruption and orthodontic movements. The study focuses on patients aged 8 to 15 years who meet specific health criteria and excludes those with certain complications or previous reconstruction failures.

Who should consider this trial

Good fit: Ideal candidates are children aged 8 to 15 years with unilateral maxillary alveolar clefts in good health.

Not a fit: Patients with bilateral alveolar clefts, cleft-associated syndromes, or systemic diseases affecting bone healing may not benefit from this study.

Why it matters

Potential benefit: If successful, this technique could significantly improve the structural integrity of the maxilla and enhance dental outcomes for children with alveolar clefts.

How similar studies have performed: While this specific approach may be novel, similar techniques in alveolar cleft reconstruction have shown promise in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients of both sexes with an age range of (eight to fifteen years), with unilateral maxillary alveolar cleft.
2. good oral hygiene and general good health

Exclusion Criteria:

1. The evidence of clinical or radiographic signs of local maxillary pathosis or palatal fistulae.
2. Those patients with bilateral alveolar clefts, cleft-associated syndromes, and those with a systemic disease that would affect either bone harvest or graft healing.
3. A history of previous failed alveolar cleft reconstruction.

Where this trial is running

Cairo and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alveolar CleftBone graftCortical- shellsRadiographic DensityHorizontal bone gainVertical bone loss
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.