Rebuilding bone in the lower back jaw with resorbable or non‑resorbable membranes
Official title: Comparative Evaluation of Resorbable (Pericardium) Versus Non Resorbable (Polytetrafluoroethylene) Membrane for Horizontal Bone Augmentation of Posterior Atrophic Mandible
Run by Beirut Arab University · NCT07254494 · Data updated 2026-11-12
This trial tests whether a resorbable pericardium membrane or a non‑resorbable PTFE membrane better helps rebuild horizontal bone in the lower back jaw for people who need bone grafting before dental implants.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Beirut Arab University Academic / other |
| Locations | 1 site (Beirut) |
| Status | Recruiting |
| Started | May 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | November 28, 2025 |
| Trial ID | NCT07254494 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with an atrophic posterior mandibular alveolar ridge needing horizontal bone augmentation before implant placement, who have adequate residual bone height, good oral hygiene, and no systemic conditions that impair bone healing are ideal candidates.
✕Probably not a fit
Patients with vertical or complex defects, active local or systemic infections, heavy smokers, poor oral hygiene, pregnancy, or systemic diseases affecting bone healing are unlikely to benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with horizontal bone loss in the posterior mandible will receive guided bone regeneration using either a resorbable pericardium membrane or a non‑resorbable PTFE membrane along with standard graft material. Outcomes such as horizontal bone gain, membrane exposure, infection, and readiness for implant placement will be tracked over follow‑up visits extending at least one year. The procedures follow routine surgical protocols for ridge augmentation and include perioperative care to minimize complications. Data will be compared between the two membrane groups to see which approach provides more predictable horizontal bone reconstruction.
Why it matters
Potential benefit: If successful, the better membrane option could provide more reliable horizontal bone gain and fewer complications, making implant placement easier and more predictable.
How similar studies have gone: Previous studies show both PTFE and resorbable membranes can support guided bone regeneration, with PTFE offering strong space maintenance but higher exposure and removal needs while resorbable pericardium often has fewer exposures, although direct head‑to‑head evidence is still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Mandibular posterior atrophic alveolar ridge Required horizontal bone augmentation procedures prior to implant placement. * Alveolar bone height suitable for implant placement. * Free of any local or systemic condition that may contraindicate ridge expansion procedure * The capacity to understand and accept the conditions of the study. * Continuing participation over at least 1 year of follow-up. Exclusion Criteria: * Heavy smokers (i.e., 2 or more packs of cigarettes per day); * Insufficient oral hygiene * Acute local or systemic infection * Patients with any systemic disease that may affect bone healing; * Pregnancy or the possibility of becoming pregnant during the study; and * Addiction to drugs or alcohol
Where it's running
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Beirut arab university
Beirut, Lebanon Recruiting
Study contacts
- Study coordinator: hiba A alrifaii, BA
- Email: haa135@student.bau.edu.lb
- Phone: 96171693913
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.