Clinical trial Recruiting at 1 site Interventional Ages 18 to 89

Reboot chronic pain with transcranial direct current stimulation (tDCS)

Official title: Reboot Pain: Integrating Neuromodulation Into Clinical Care for Military and Veterans With Chronic Pain

Run by Emory University · NCT07411859 · Data updated 2026-11-12

This program will try daily, short tDCS sessions alongside Emory's Accelerated Behavioral Health Program to see if it reduces chronic pain in adult service members and veterans.

Quick facts

Study typeInterventional
Ages18 Years to 89 Years
SexAll
Enrollment100 (estimated)
SponsorEmory University
Academic / other
Locations1 site (Atlanta, Georgia)
StatusRecruiting
StartedFebruary 16, 2026
Main results expectedMay 2027
Study endsMay 2027
Registry record updatedApril 14, 2026
Trial IDNCT07411859 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adult service members or veterans (18–89) enrolled in Emory's ABHP who report moderate-to-severe chronic pain (PEG ≥ 4), have an established primary care or pain provider, and have no contraindications are ideal candidates.

Probably not a fit

People with implanted pacemakers, seizure disorders, current use of excluded medications, new neurologic symptoms, pregnancy, or those not enrolled in Emory's ABHP are unlikely to be eligible or benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This protocol adds non-drug brain stimulation (tDCS) to standard mental health care in the Emory Healthcare Veterans Program Accelerated Behavioral Health Program (ABHP) to target chronic pain. Adult service members and veterans (ages 18–89) enrolled in ABHP will self-administer roughly 20-minute tDCS sessions daily for two weeks, either in person at Emory's Executive Park Clinic or virtually with support. Pain will be tracked with the PEG scale, daily surveys, questionnaires, and standard clinical interviews, with follow-up assessments at 3, 6, and 12 months. Participants with implanted devices, seizure disorders, certain medications, pregnancy, or new neurologic symptoms are excluded due to safety concerns.

Why it matters

Potential benefit: If successful, adding tDCS to behavioral care could lower chronic pain and improve daily function without adding medications.

How similar studies have gone: Prior small trials of tDCS for chronic pain have shown mixed but occasionally promising results, so the approach has some supportive evidence but is not yet definitively proven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female, 18-89 years old
* Treated on site for ABHP
* Willing to self-administer tDCS and complete the measures
* PEG pain intensity of 4 or more for most of the day at least 3 days per week
* Have an established PCP (Primary Care Provider) or pain management provider

Exclusion Criteria:

* Implanted pacemaker
* Seizure Disorder
* Pregnancy, if applicable
* Any new onset of the following:

  * Balance Problems
  * Difficulty walking
  * Bladder incontinence
  * Bowel incontinence
  * Numbness
  * Tingling
  * Weakness
* Medical contraindications

  * Current use of sodium channel blockers
  * Lidocaine (OTC/transdermal delivery is ok)
  * Mexiletine
  * Amitriptyline; other tricyclic antidepressants
  * Anti-epileptic medications: phenytoin, carbamazepine, lamotrigine, oxcarbazepine, rufinamide, lacosamide and eslicarbazepine acetate

    * Current use of calcium channel blockers
    * Current use of N-Methyl-D-aspartate receptor antagonists
  * Ketamine
  * Dextromethorphan
  * Felbamate

    * History of brain surgery
    * History of brain tumor
    * History of seizure disorder
    * History of stroke
    * Intracranial metal implantation
* Adults unable to consent
* Individuals who are not yet adults
* Prisoners
* Non-English speaking

Where it's running

  • The Emory Clinic
    Atlanta, Georgia, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.