Real-time prediction model for acute kidney injury in hospitalized patients
Development and Validation of a Real-time Prediction Model for Acute Kidney Injury in Hospitalized Patients
This study is testing a new tool that uses data to predict acute kidney injury in hospitalized patients, helping doctors act quickly to prevent it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 161876 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Peking University First Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06597838 on ClinicalTrials.gov |
What this trial studies
This study focuses on developing and validating a real-time prediction model for acute kidney injury (AKI) specifically for hospitalized patients in developing countries. The model utilizes machine learning techniques to analyze data from a large tertiary hospital in China and aims to provide early warnings for AKI, potentially allowing for timely interventions. The model's effectiveness will be validated across five independent hospitals in different geographic locations within China to ensure its reliability and applicability in diverse settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients aged 18 years and older who are admitted to the participating hospitals.
Not a fit: Patients with end-stage renal disease, those on dialysis, or who have had prior AKI are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this model could significantly reduce the incidence of acute kidney injury in hospitalized patients, leading to better patient outcomes and reduced healthcare costs.
How similar studies have performed: While there have been various prediction models for AKI, this specific approach targeting general hospitalized patients in developing countries is novel and has not been previously published.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (18 years and older) admitted to five hospitals during the study period Exclusion Criteria: * Have less than 2 documented serum creatinine (Scr) measurements during hospitalization * Being diagnosed with end-stage renal disease (ESRD) * Maintained on dialysis or had an initial Scr greater than or equal to 4.0 mg/dL at admission * Developed AKI prior to admission or within 24 hours after admission * Length of stay shorter than 24 hours * Underwent kidney transplantation or nephrectomy during hospitalization * With all Scr measurements lower than or equal to 0.6 mg/dL from 90 days prior to admission until discharge.
Where this trial is running
Beijing, Beijing Municipality
- Peking University First Hospital — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Yuhui Zhang
- Email: 451076336@qq.com
- Phone: +86 18813037026
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.