Real-time analysis of colorectal ulcers using a computer-aided system
Construction and Validation of a Computer-aided (CADx）System in Real-time Characterization of Colorectal Ulcerative Diseases: A Multicenter, Retrospective Study
This study is testing a new computer system that helps doctors better understand and identify different types of colorectal ulcers during colonoscopy exams.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Nanfang Hospital, Southern Medical University Academic / other |
| Locations | 1 site (Guangzhou, Undefined) |
| Trial ID | NCT06208982 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop and validate a Computer-aided (CADx) system for the real-time characterization of colorectal ulcerative diseases. It involves a multi-center, retrospective analysis of colonoscopy images and videos of various colorectal ulcers, including cancer and inflammatory diseases. The study will create a training cohort from the majority of cases and a validation cohort from the remaining cases to assess the diagnostic accuracy of the CADx system. Data collected will include demographics, laboratory results, and detailed endoscopic findings, all while ensuring patient confidentiality.
Who should consider this trial
Good fit: Ideal candidates are individuals who have undergone endoscopic examination and have documented ulcerative lesions in the large intestine.
Not a fit: Patients with poor quality endoscopic images or incomplete medical records may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the diagnostic accuracy and efficiency in identifying colorectal ulcerative diseases, leading to better patient outcomes.
How similar studies have performed: Other studies utilizing computer-aided diagnostic systems have shown promising results, indicating potential success for this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. They underwent endoscopic examination and are found to have ulcerative lesions in the large intestine; 2. They have endoscopic images and videos captured and stored during colonoscopy which are available to be retrieved; 3. They have the complete medical records and clear diagnosis. Exclusion Criteria: 1)Poor quality endoscopic images and videos defined as: 1. Incomplete visualization of the colorectal ulcer due to technical reasons (e.g. out-of-focus, motion-blurred or insufficient illumination); 2. Artifacts due to mucus, air bubbles, stool, or blood. 2)Obscured view due to poor bowel preparation; 3)Incomplete medical record; 4)Prior history of intestinal resection, fistula, or anastomosis.
Where this trial is running
Guangzhou, Undefined
- Nanfang Hospital, Southern Medical University — Guangzhou, Undefined, China (Recruiting)
Study contacts
- Study coordinator: Xiaobei Luo, PhD
- Email: luoxiaobei63@126.com
- Phone: 17688881428
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.