Rapid autopsy program for small cell lung cancer patients
Official title: Rapid ("Warm") Autopsy Protocol for Patients With Small Cell Lung Cancer
Run by Indiana University · NCT05889546 · Data updated 2026-11-12
This study is trying to set up a quick way to collect and analyze tumor samples from small cell lung cancer patients after they pass away to help find important markers for the disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 3 sites (Indianapolis, Indiana and 2 other locations) |
| Status | Recruiting |
| Started | August 31, 2022 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2031 |
| Registry record updated | July 14, 2026 |
| Trial ID | NCT05889546 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have an active diagnosis of small cell lung cancer.
✕Probably not a fit
Patients who do not have a diagnosis of small cell lung cancer or are under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot project aims to establish a rapid autopsy program specifically for patients with small cell lung cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center. The study involves collaboration among scientists, lung cancer physicians, and pathologists to outline the necessary components for tumor tissue collection. The collected tumor tissues will be utilized for various analyses, including protein and gene analysis, RNA sequencing, and whole exome sequencing, contributing to the identification of biological and molecular markers of SCLC.
Why it matters
Potential benefit: If successful, this program could enhance our understanding of small cell lung cancer and lead to improved diagnostic and therapeutic strategies.
How similar studies have gone: While rapid autopsy programs have been explored in other cancer types, this specific approach for small cell lung cancer is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ≥ 18 years old at the time of informed consent 2. Written informed consent and HIPAA authorization for release of personal health information. 3. Active SCLC diagnosis.
Where it's running
-
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States Recruiting -
Roudebush VA Medical Center
Indianapolis, Indiana, United States Recruiting -
Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana, United States Recruiting
Study contacts
- Principal investigator: Shadia I. Jalal, MD — Indiana University
- Study coordinator: Gabby Kline, BA
- Email: gabkline@iu.edu
- Phone: (317) 278-2514
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.