Rapid autopsy program for small cell lung cancer patients
Rapid ("Warm") Autopsy Protocol for Patients With Small Cell Lung Cancer
This study is trying to set up a quick way to collect and analyze tumor samples from small cell lung cancer patients after they pass away to help find important markers for the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 3 sites (Indianapolis, Indiana and 2 other locations) |
| Trial ID | NCT05889546 on ClinicalTrials.gov |
What this trial studies
This pilot project aims to establish a rapid autopsy program specifically for patients with small cell lung cancer (SCLC) at the Indiana University Simon Comprehensive Cancer Center. The study involves collaboration among scientists, lung cancer physicians, and pathologists to outline the necessary components for tumor tissue collection. The collected tumor tissues will be utilized for various analyses, including protein and gene analysis, RNA sequencing, and whole exome sequencing, contributing to the identification of biological and molecular markers of SCLC.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have an active diagnosis of small cell lung cancer.
Not a fit: Patients who do not have a diagnosis of small cell lung cancer or are under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could enhance our understanding of small cell lung cancer and lead to improved diagnostic and therapeutic strategies.
How similar studies have performed: While rapid autopsy programs have been explored in other cancer types, this specific approach for small cell lung cancer is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ≥ 18 years old at the time of informed consent 2. Written informed consent and HIPAA authorization for release of personal health information. 3. Active SCLC diagnosis.
Where this trial is running
Indianapolis, Indiana and 2 other locations
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center — Indianapolis, Indiana, United States (Recruiting)
- Roudebush VA Medical Center — Indianapolis, Indiana, United States (Recruiting)
- Sidney and Lois Eskenazi Hospital — Indianapolis, Indiana, United States (Recruiting)
Study contacts
- Principal investigator: Shadia I. Jalal, MD — Indiana University
- Study coordinator: Gabby Kline, BA
- Email: gabkline@iu.edu
- Phone: (317) 278-2514
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.