Radiofrequency combined with ultrasound for postpartum sexual pain

Effectiveness of Combined Monopolar Radiofrequency and Ultrasound (BTL EXILIS ULTRA 360™) for the Improvement of Dyspareunia Caused by Postpartum Scarring in Women of Childbearing Age: A Study Protoco

Not applicable Interventional Institut Investigacio Sanitaria Pere Virgili · NCT07504991

This study will try a combined radiofrequency and ultrasound treatment (BTL Exilis) to reduce pain during sex in women who developed dyspareunia after a vaginal delivery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment34 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorInstitut Investigacio Sanitaria Pere Virgili Academic / other
Locations1 site (Tarragona, TARRAGONA)
Trial IDNCT07504991 on ClinicalTrials.gov

What this trial studies

This is a community-based, non-randomized, quasi-experimental study delivering monopolar radiofrequency combined with ultrasound (BTL Exilis) to women with dyspareunia following at least one vaginal delivery that involved a tear or episiotomy. Pain during penetrative intercourse will be measured before and after treatment in the same individuals using the Visual Analogue Scale (VAS), with moderate-to-severe pain defined as VAS ≥4. There is no randomized control group; the primary outcome is resolution or reduction of pain during sexual intercourse after completing the treatment. The trial is conducted at Centro Procrear in Tarragona and requires informed consent and clinical confirmation of postpartum dyspareunia.

Who should consider this trial

Good fit: Women of childbearing age with at least one prior vaginal delivery involving a tear or episiotomy, persistent moderate-to-severe dyspareunia (VAS ≥4), and no contraindications to radiofrequency/ultrasound are ideal candidates.

Not a fit: Patients with non-postpartum causes of dyspareunia, mild pain (VAS <4), underlying pelvic pathology causing pain, or medical contraindications to the device are unlikely to benefit.

Why it matters

Potential benefit: If successful, the treatment could reduce or eliminate pain during intercourse and improve sexual function and quality of life for affected women.

How similar studies have performed: Energy-based vaginal therapies including radiofrequency have been used for vaginal laxity and sexual symptoms with mixed and limited high-quality evidence, and specific data for postpartum dyspareunia are sparse.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women of childbearing age
* Medical history of at least one prior vaginal delivery
* Reported persistent pain during penetrative sexual intercourse
* Meeting the clinical criteria for dyspareunia
* Moderate to severe pain level, defined as a score of 4 or higher on the Visual Analogue Scale (VAS 0-10)
* Eligible patients must demonstrate a moderate to severe pain level, defined as a VAS score of 4 or higher
* No restriction on the time elapsed between the last delivery and the current clinical diagnosis.

Exclusion Criteria:

* Contraindications to the study treatment. Women with any medical condition that precludes the use of the study technology
* Non-postpartum dyspareunia

Where this trial is running

Tarragona, TARRAGONA

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dyspareuniavaginal deliverydyspareuniaradiofrequencyperineumVisual Analogue Scaletear scarepisiotomy scar
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.