Quercetin's effects on endometriosis outcomes
Effect of Quercetin Supplementation on Glycemic Status, Lipid Profile, Oxidative Stress, Inflammation, Growth Factor, Adiponectin, Sex Hormones and Anthropometric Indices in Women With Endometriosis
This study is testing if taking quercetin can improve health outcomes for women with endometriosis compared to a placebo over twelve weeks.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | National Nutrition and Food Technology Institute Academic / other |
| Locations | 1 site (Tehran) |
| Trial ID | NCT05983224 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of quercetin supplementation on women diagnosed with endometriosis. Participants will be randomly assigned to receive either quercetin or a placebo for twelve weeks, with blood samples collected before and after the intervention to assess various health indicators. The study aims to evaluate changes in glycemic status, lipid profile, inflammation, and sex hormones among other factors. This is the first study of its kind to explore quercetin's effects on endometriosis in Iran and globally.
Who should consider this trial
Good fit: Ideal candidates are women aged 18 to 40 with a confirmed diagnosis of endometriosis and a regular menstrual cycle.
Not a fit: Patients using hormonal medications or with immune disorders, persistent infections, or other uterine conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new dietary supplement option for managing endometriosis symptoms.
How similar studies have performed: While quercetin has shown promise in reducing endometriosis cell proliferation in previous studies, this specific approach has not been tested in clinical settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing to cooperate and complete the informed consent form. * Diagnosed endometriosis using laparoscopy and histopathological tests. * In the age group of 18 to 40 years. * Having a regular menstrual cycle. * Having a body mass index between 18.5 and 30. Exclusion Criteria: * Using hormonal medications or intrauterine treatments for a minimum of three months prior to collecting a sample. * Having immune system disorders, persistent infections, diabetes, or any conditions like polyps and fibroids within the uterine cavity.
Where this trial is running
Tehran
- National Nutrition and Food Technology Research Institute — Tehran, Iran, Islamic Republic of (Recruiting)
Study contacts
- Principal investigator: Ghazaleh Eslamian, PhD — National Nutrition and Food Technology Research Institute
- Study coordinator: Ghazaleh Eslamian, PhD
- Email: gh_eslamian@yahoo.com
- Phone: +989122173918
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.