Quality control of MRI screening for those at high risk of pancreatic cancer
Quality Control Study of MR Based Screening of Individual With Increased Risk for Pancreas Cancer
This study looks at whether regular MRI screenings can help people with a family history of pancreatic cancer catch early signs of the disease and improve their chances of survival.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Karolinska University Hospital Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT02078245 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the early detection of pre-cancerous lesions and early-stage pancreatic cancer in individuals with a significant genetic predisposition. Following Swedish guidelines, patients with a family history of pancreatic cancer underwent clinical surveillance using Magnetic Resonance Imaging (MRI). The study analyzes the results from patient files collected during the screening period to assess the effectiveness of this approach in improving survival rates.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with a family history of pancreatic cancer who have a tenfold increased risk of developing the disease.
Not a fit: Patients under 18 years of age or those who cannot provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and better survival outcomes for patients at high risk of pancreatic cancer.
How similar studies have performed: Other studies have shown promising results in early detection of pancreatic cancer through similar surveillance approaches, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 10 fold higher risk to develop pancreatic cancer * Obtained informed consent Exclusion Criteria: * age less than 18 yrs * No consensus obtained
Where this trial is running
Stockholm
- Gastrocentrum Karolinska University Hospital — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Marco del Chiaro, ass. prof. — Karolinska University Hospital
- Study coordinator: Matthias Löhr, Professor
- Email: matthias.lohr@ki.se
- Phone: +46 8-585800000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.