Qishenyiqi Dripping Pill for treating Coronary Microvascular Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the efficacy and safety of Qishenyiqi dripping pills in patients suffering from microvascular angina pectoris. Participants will receive either the Qishenyiqi treatment or a placebo, with a regimen of one bag three times a day. The study includes a long-term follow-up period of one year to assess the impact of the treatment on coronary flow reserve and the occurrence of adverse cardiovascular events. The trial aims to provide insights into the potential benefits of this traditional Chinese medicine for coronary microvascular disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Repeated chest pain attacks with typical exertional angina pectoris or resting angina pectoris attacks;
* Coronary normal or stenosis \< 20%;
* Ischemic depression in ST segment during resting or exercise;
* Blood flow reserve (CFR) of the anterior descending coronary artery \< 2.0;
* Subjects or their guardians agreed to participate in this study.

Exclusion Criteria:

* Previous myocardial infarction or PCI or CABG treatment;
* A history of heart failure;
* Severe arrhythmia;
* Refractory hypertension or hypertension accompanied by left ventricular wall thickness \> 12 mm;
* Familial hypercholesterolemia;
* Takayasu arteritis, Kawasaki disease or coronary artery malformation;
* Pregnant or nursing, or having the intention to give birth within one year;
* Hepatic or renal dysfunction;
* Allergic to contrast agents or traditional Chinese medicines;
* Patients who participated in clinical research of other drugs within 3 months before being selected.

Where it's running

• Qilu Hospital of Shandong University
  Jinan, Shandong, China Recruiting
• Jinan Central Hospital Affiliated to Shandong First Medical University
  Jinan, Shandong, China Recruiting
• Qianfoshan Hospital, Shandong University
  Jinan, Shandong, China Active not recruiting

Study contacts

• Study coordinator: Panpan Hao, Dr.
• Email: panda.how@sdu.edu.cn
• Phone: 8618560086593

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study looks at patients with coronary microvascular disease to see how the condition develops and affects their quality of life and heart health.

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• Improving heart blood flow and angina in women using an SGLT2 pill (STRONG)

  This trial will test whether taking the SGLT2 pill Brezavvy for 12 weeks can improve coronary microvascular blood flow and reduce angina symptoms in women with non-obstructive coronary artery disease.

  Recruiting Phase 1 University of Virginia · Charlottesville, Virginia · NCT06600178

• Exercise training for patients with chest pain and no blocked arteries

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  Recruiting Bispebjerg Hospital · Copenhagen and 1 other locations · NCT06529848

• Registry collecting data on microvascular dysfunction and coronary spasm

  This study is collecting information from patients with microvascular dysfunction and coronary spasm to better understand their experiences and improve their care.

  Recruiting Johannes Gutenberg University Mainz · Mainz, Rhineland-Palatinate · NCT06125392

• Understanding how heart conditions affect tolerance to rapid heart rates

  This study is testing how well people with heart conditions, especially those with coronary artery disease, can handle fast heart rates and whether treating their condition with stents can help them tolerate it better.

  Recruiting Imperial College London · London · NCT05841199

• Using fundus imaging to identify coronary microvascular disease

  This study is testing if special eye imaging can help find heart problems related to small blood vessels in people who have normal coronary arteries.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT05743140

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.