Pulpotomy treatment for painful primary molars in children
Official title: Treatment Outcomes of Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis: An International Multi-centre Study
Run by Qatar University · NCT06149845 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if a less invasive tooth treatment called pulpotomy can help relieve pain and save primary molars in children aged 4 to 9 with serious tooth issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 4 Years to 9 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Qatar University Academic / other |
| Locations | 2 sites (Doha and 1 other locations) |
| Trial ID | NCT06149845 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy children aged 4 to 9 years with vital primary molars showing symptoms of irreversible pulpitis.
✕Probably not a fit
Patients with signs of pulpal infection or significant periapical radiolucency will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of pulpotomy as a treatment for vital primary molars diagnosed with symptomatic irreversible pulpitis in children aged 4 to 9 years. Pulpotomy is a less invasive alternative to the traditional pulpectomy, aiming to preserve the tooth while alleviating pain. The study will assess clinical and radiographic outcomes over one and two years, focusing on success rates and post-operative pain relief. Participants will be recruited from pediatric dental clinics across eight countries, ensuring a diverse patient population.
Why it matters
Potential benefit: If successful, this treatment could provide a less invasive and more effective option for managing painful primary molars in children.
How similar studies have gone: While pulpotomy has been successfully used in permanent teeth, this approach for primary teeth is relatively novel and has limited prior research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Healthy (ASA I and II) co-operative children (Frankl Scale + and ++) between the ages of four and nine years. 2. Participants have symptoms typical of irreversible pulpitis in one of the primary molars. 3. The pulp of the affected primary molar is vital. 4. Radicular pulp health is confirmed by attainment of radicular pulp haemostasis within 6 minutes of coronal pulp amputation. 5. The affected primary molars can be restored with full coverage crowns. 6. Any physiologic root resorption, if present, is less than ⅓ the root length Exclusion Criteria: 1. Clinical examination of affected primary molar reveals signs of pulpal infection (e.g. pathologic tooth mobility, parulis/fistula, or soft tissue swelling) 2. Pre-operative periapical radiograph suggests presence of periapical radiolucency. 3. Pre-operative periapical radiograph suggests presence of furcal radiolucency more than ½ the furcation to periapical area. 4. Visual examination of pulp tissue after deroofing reveals signs of necrosis (e.g. avascular/minimally bleeding pulp tissue or yellowish necrotic areas/purulent exudate). 5. Signs of extensive radicular pulp inflammation. 6. Parents not willing to place full coverage crowns post-pulpotomy. 7. Clinical diagnosis of irreversible pulpitis between two teeth is not sharply defined.
Where it's running
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Phcc - Airport Center
Doha, Qatar Recruiting -
PHCC- Leebaib Center
Doha, Qatar Recruiting
Study contacts
- Principal investigator: Nebu Philip, PhD — Qatar University
- Study coordinator: Nebu Philip, PhD
- Email: nphilip@qu.edu.qa
- Phone: +974-44037319
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Impact of a 1-file rotary system on debris extrusion during root canal treatment
This study tests whether using a single-file AF One system during root canal shaping reduces postoperative discomfort in teeth with irreversible pulpitis and mature roots.
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Single Rotary File System vs Manual Instrumentation for Pulpectomy in Primary Molars
This trial tests whether using a single rotary file system for pulpectomy in primary molars changes how children behave during the procedure compared with traditional manual instruments.
-
Complete pulpotomy versus root canal for irreversible pulpitis in adults with Type 2 diabetes
This will test whether complete pulpotomy or root canal treatment better preserves symptom-free, functional mature back teeth with irreversible pulpitis in adults who have Type 2 diabetes.
-
Evaluating the effectiveness of pulpotomy for treating deep caries in permanent teeth
This study is testing how well pulpotomy treatments work for adults with deep tooth decay to see if they can keep their teeth healthy and pain-free.
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Pulpotomy vs Pulpectomy for painful baby teeth in children
This study tests whether pulpotomy can work as well as pulpectomy for treating painful, living primary molars in kids aged 4–9.
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Evaluating the success of vital pulp therapy methods for dental pulp exposure
This study is testing different ways to treat exposed dental pulp to see which methods work best for adults with teeth that can be saved.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.