Psychological distress and its effects on treatment adherence, outcomes, and quality of life in people with cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, longitudinal study enrolling adults with confirmed malignant tumors who are planning to receive or are receiving systemic cancer treatment. Participants will complete GAD-7 and PHQ-9 questionnaires to measure anxiety and depression, while treatment adherence, clinical outcomes, and quality-of-life measures are recorded during a 3-year follow-up. No experimental interventions are given; the study examines natural variation in psychological distress and links it to adherence and outcomes. Results aim to clarify associations that could inform supportive care and follow-up strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* (1) Confirmed malignant tumors by imaging or pathology (such as hepatobiliary carcinoma, gastric cancer, breast cancer, lung cancer, etc.)
* (2) Planning to receive or currently undergoing systemic treatment (such as surgery, chemotherapy, TACE, targeted therapy, etc.)
* (3) Age ≥18 years old
* (4) Sign the informed consent form and voluntarily participate in this study

Exclusion Criteria:

* (1) Combined with severe systemic diseases (such as severe cardiovascular and cerebrovascular diseases)
* (2) There is severe cognitive impairment and it is impossible to complete the questionnaire assessment
* (3) Incomplete clinical data or loss to follow-up

Where it's running

• First Affiliated Hospital of Wenzhou Medical University
  Wenzhou, Zhejiang, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.