Psychiatric symptoms in people with White‑Sutton syndrome
Official title: Descriptive Study of Psychiatric Symptoms in White-Sutton Syndrome
Run by Centre Hospitalier Universitaire Dijon · NCT07380594 · Data updated 2026-11-12
This project will describe psychiatric symptoms in children and adults with White‑Sutton syndrome using interviews and questionnaires to better understand common mental health issues.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 1 site (Dijon) |
| Status | Recruiting |
| Started | January 2026 |
| Main results expected | January 2028 |
| Study ends | January 2028 |
| Registry record updated | February 2, 2026 |
| Trial ID | NCT07380594 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are French‑speaking individuals aged over 6 years with genetically confirmed White‑Sutton syndrome (POGZ mutation) who, or whose carers, can complete a 1–2 hour questionnaire and provide consent.
✕Probably not a fit
Patients without genetic confirmation, non‑French speakers, children under 6, those unable to complete remote or phone interviews, or those who refuse consent are unlikely to participate or benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project collects psychiatric information from French‑speaking individuals with genetically confirmed White‑Sutton syndrome using interviews and standardized questionnaires, conducted by phone, videoconference, or in person at CHU Dijon. Eligible participants are aged over 6 years and can complete a 1–2 hour questionnaire themselves or with a caregiver. The protocol documents anxiety, autism spectrum features, attention and behavioral problems, sleep and seizure‑related psychiatric manifestations, and other neuropsychiatric signs. Collected data will characterize symptom frequency and heterogeneity to improve clinical recognition and inform future research on interventions.
Why it matters
Potential benefit: If successful, the results could help clinicians better recognize common psychiatric features in White‑Sutton syndrome and guide more tailored care and future treatment research.
How similar studies have gone: Previous small descriptive reports have reported predominant anxiety and variable autism, attention, and behavioral features, but systematic, larger-scale data are still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with White Sutton syndrome (genetic mutation identified by genetic testing) adults and children, and French speakers * Patient or carer able to complete a questionnaire in French lasting 1 to 2 hours * Age \> 6 years (lower age limit for the primary endpoint) * Consent of the patient (and their parents if the patient is a minor) and legal representative (for patients under guardianship or trusteeship) to participate in the study Exclusion Criteria: * Absence of genetic confirmation of the diagnosis * Refusal by parents or legal representatives to participate or authorise the use of data for research purposes * Technical impossibility of conducting the interview by videoconference or telephone * Unfeasible protocol * patient interruption
Where it's running
-
CHU Dijon Bourgogne
Dijon, France Recruiting
Study contacts
- Study coordinator: Raphaëlle MOTTOLESE
- Email: raphaelle.mottolese@chu-dijon.fr
- Phone: 03 80 29 53 13
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.