Psoriasis rapid-response observation of new therapies in real-world practice

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This non-interventional cohort follows adults starting a new advanced therapy for moderate-to-severe plaque psoriasis. Data are collected from patients and their dermatologists at baseline and at 2, 4, and 16 weeks after treatment initiation. The study uses standardized tools to capture clinical status, patient-reported outcomes, and medication use. It aims to describe outcomes, support clinical decision making, and characterize baseline patient factors and, when present, psoriatic arthritis symptoms. Enrollment requires in-person follow-up visits and informed consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

The inclusion criteria for this study will be as follows:

1. Patient is at least 18 years of age at the time of study enrollment
2. Patient has a diagnosis of moderate to severe plaque psoriasis based on an Investigator Global Assessment (IGA, part of routine care) score of 3 or 4 at the time of Enrollment.
3. Patient is initiating new Eligible Medication for the first time for the treatment of PSO.
4. Patient is willing and able to provide informed consent to participate in this study.
5. Patient is willing to be seen in-person by their treating dermatology provider at two (2), four (4), and sixteen (16) weeks following initiation of the advanced therapy.

Exclusion Criteria:

An individual who meets any of the following criteria will be excluded from participation in the study:

1. Patient is participating in a blinded clinical trial.
2. Patients that do not receive at least 1 dose of the advanced therapy within 14 days following the Enrollment/Baseline visit for the study.
3. Patients cannot be concurrently enrolled in both the CorEvitas PSO Registry and the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study.

A. Patients currently enrolled in the CorEvitas PSO Registry are ineligible for participation in the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study.

B. Patients otherwise meeting eligibility criteria can be enrolled in the CorEvitas Psoriasis (PSO) Rapid Response Non-Interventional Study C. Following completion or at time of Exit from the CorEvitas Psoriasis (PSO) Rapid Response Non Interventional Study, patients will be eligible to enroll into the CorEvitas PSO Registry for long term follow up at the standard of care cadence supported by the registry. A separate Informed consent will be obtained.

Where it's running

• CorEvitas, LLC
  Waltham, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Psoriasis Rapid Response Study Team
• Email: ppd_corepsoriasis@thermofisher.com
• Phone: 6178655932

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.