PRP pharmacopuncture for chronic neck pain from upper trapezius myofascial syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, placebo‑controlled interventional trial comparing a single PRP pharmacopuncture treatment to normal saline pharmacopuncture in adults with chronic neck pain from upper trapezius myofascial syndrome. Sixty participants aged 18–59 with chronic neck pain (>3 months) and a VAS activity score of 30–70 mm will be enrolled and randomly assigned to PRP or placebo. Outcomes include pain, function, quality of life, and adverse events measured at 2, 4, and 8 weeks after the intervention. The trial focuses on localized trigger‑point treatment and uses standardized follow-up assessments to detect short‑term benefits and safety signals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female, aged 18 to 59 years.
* Experiencing neck pain for more than 3 months (chronic).
* Neck pain classified as Grade I to III according to the Neck Pain Task Force classification.
* Presence of referred pain pattern on physical examination consistent with the distribution of the upper trapezius muscle.
* Visual Analogue Scale (VAS) score between 30 and 70 mm (out of 100 mm) during activity (e.g., daily activities or light exercise).
* Willing to participate in the study until completion and has signed the informed consent form.

Exclusion Criteria:

* Hemoglobin level \<13 g/dL for males or \<12 g/dL for females.
* Platelet count \<150,000/μL.
* Presence of fever (≥37.5°C).
* Diagnosis of fibromyalgia.
* Structural abnormalities of the cervical spine other than degenerative changes, such as fractures, cervical spine injuries, space-occupying lesions (SOL), infections, neoplasms, or systemic diseases confirmed by radiographic imaging.
* History of cervical spine surgery.
* Presence of tumors, wounds, or skin infections at the needle insertion site.
* Diagnosed with blood disorders or currently taking anticoagulant or antiplatelet medications.
* History of hypersensitivity reactions to acupuncture (e.g., metal allergy, severe atopy, keloids, or other skin hypersensitivities).
* Uncontrolled cardiovascular disease or diabetes mellitus.
* History of pharmacopuncture therapy to the upper trapezius muscle within the past 6 months.
* Use of anti-inflammatory medication within the past 2 weeks.
* Currently pregnant or breastfeeding.

Where it's running

• Fakultas Kedokteran Universitas Indonesia
  Jakarta, Indonesia Recruiting

Study contacts

• Principal investigator: Kepk Fkui-Rscm — The Ethics Committee of the Faculty of Medicine, University of Indonesia - RSCM
• Study coordinator: Irma Nareswari, MD
• Email: i.nareswarifkuirscm@yahoo.com
• Phone: +6281267793888

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.