Clinical trial Recruiting at 1 site Interventional Ages 45 and up

Promoting safer diabetes treatments for older adults

Official title: Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Run by University Hospitals Cleveland Medical Center · NCT05933174 · Data updated 2026-11-12

This study is testing ways to help older adults with type 2 diabetes safely switch from sulfonylureas to better treatment options by encouraging conversations with their doctors.

More Type2diabetes trials

Quick facts

Study typeInterventional
Ages45 Years and up
SexAll
Enrollment220 (estimated)
SponsorUniversity Hospitals Cleveland Medical Center
Academic / other
Locations1 site (Cleveland, Ohio)
StatusRecruiting
StartedOctober 1, 2023
Main results expectedJune 30, 2027
Study endsJune 30, 2027
Registry record updatedSeptember 4, 2026
Trial IDNCT05933174 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 45 and older with type 2 diabetes currently prescribed sulfonylureas.

Probably not a fit

Patients with type 1 diabetes or those unable to engage in discussions about their treatment options may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to improve patient safety for older adults with type 2 diabetes who are currently prescribed sulfonylureas, a class of medications associated with adverse effects. The researchers will identify patients aged 45 and older taking sulfonylureas and empower them to discuss alternative treatments with their primary care providers. Additionally, primary care providers will receive education on contemporary diabetes treatment guidelines and the risks and benefits of various medication classes. The goal is to facilitate informed discussions and promote safer treatment options in ambulatory settings.

Why it matters

Potential benefit: If successful, this approach could lead to safer diabetes management and reduced adverse effects for older patients.

How similar studies have gone: Other studies have shown success in promoting safer medication alternatives in diabetes care, making this approach both relevant and necessary.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 45 years
* Type 2 diabetes (diagnosed on or before 12/31/2021)
* Current/active prescription for one or more SU medications
* Established care (≥2 visits) with UH primary care provider (PCP) since 2021

Exclusion Criteria:

* Type 1 diabetes
* PCP provides a reason why patient participation is inappropriate (e.g., known cost barriers without any alternatives, prior discussion with patient about alternatives, etc.)
* Patient unable or unwilling to have conversation with their PCP regarding SU
* Unable to provide informed consent

Where it's running

  • University Hospitals Cleveland Medical Center
    Cleveland, Ohio, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.