Promoting safer diabetes treatments for older adults
Official title: Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes
Run by University Hospitals Cleveland Medical Center · NCT05933174 · Data updated 2026-11-12
This study is testing ways to help older adults with type 2 diabetes safely switch from sulfonylureas to better treatment options by encouraging conversations with their doctors.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years and up |
| Sex | All |
| Enrollment | 220 (estimated) |
| Sponsor | University Hospitals Cleveland Medical Center Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT05933174 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 45 and older with type 2 diabetes currently prescribed sulfonylureas.
✕Probably not a fit
Patients with type 1 diabetes or those unable to engage in discussions about their treatment options may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to improve patient safety for older adults with type 2 diabetes who are currently prescribed sulfonylureas, a class of medications associated with adverse effects. The researchers will identify patients aged 45 and older taking sulfonylureas and empower them to discuss alternative treatments with their primary care providers. Additionally, primary care providers will receive education on contemporary diabetes treatment guidelines and the risks and benefits of various medication classes. The goal is to facilitate informed discussions and promote safer treatment options in ambulatory settings.
Why it matters
Potential benefit: If successful, this approach could lead to safer diabetes management and reduced adverse effects for older patients.
How similar studies have gone: Other studies have shown success in promoting safer medication alternatives in diabetes care, making this approach both relevant and necessary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 45 years * Type 2 diabetes (diagnosed on or before 12/31/2021) * Current/active prescription for one or more SU medications * Established care (≥2 visits) with UH primary care provider (PCP) since 2021 Exclusion Criteria: * Type 1 diabetes * PCP provides a reason why patient participation is inappropriate (e.g., known cost barriers without any alternatives, prior discussion with patient about alternatives, etc.) * Patient unable or unwilling to have conversation with their PCP regarding SU * Unable to provide informed consent
Where it's running
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States Recruiting
Study contacts
- Principal investigator: Ian Neeland, MD — University Hospital Cleveland Medical Center
- Study coordinator: Ian Neeland, MD
- Email: ian.neeland@uhhospitals.org
- Phone: 216-844-5965
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.