Prolonged compression after foam sclerotherapy for varicose veins

Prolonged Compression Therapy Following Foam Sclerotherapy of Varicose Veins

This study tests whether wearing compression stockings for one month or one week after foam sclerotherapy helps people with varicose veins have better results and fewer side effects.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 140 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Pirogov Russian National Research Medical University (Academic / other)
• Locations: 1 site (Moscow)
• Trial ID: NCT06766968 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of prolonged compression therapy following foam sclerotherapy for treating varicose veins. Participants will be assigned to wear graduated compression stockings for either one month or one week after the sclerotherapy procedure. The study aims to evaluate the impact of different durations of compression on the incidence of skin hyperpigmentation and other adverse effects. By comparing these two approaches, the trial seeks to determine the optimal compression duration to enhance treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years with clinical class C2 varicose veins scheduled for foam sclerotherapy.

Not a fit: Patients with a history of deep vein thrombosis or those requiring long-term compression therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management of varicose veins and reduced side effects for patients undergoing sclerotherapy.

How similar studies have performed: Previous studies have shown varying success with compression therapy in similar contexts, but this specific approach is novel.

Eligibility criteria

Inclusion Criteria:

* Age over 18 years;
* Varicose veins of the lower extremities of clinical class C2 according to CEAP classification;
* Scheduled foam-form sclerotherapy of varicose tributaries as an independent intervention or after trunkal ablation;
* Absence of initial skin pigmentation, including that associated with previously performed trunk ablation;
* Absence of indications for long-term use of compression therapy, including the clinical class of chronic venous disease C3-C6 and persistence of vein-specific symptoms;
* Signed informed consent to participate in the study.

Exclusion Criteria:

* History of deep vein thrombosis;
* Contraindications or restrictions to foam-form sclerotherapy;
* Contraindications or restrictions to long-term use of compression therapy;
* Inability or difficulty in independently putting on MCS;
* Refusal to participate in the study.

Where this trial is running

Moscow

• MedSwiss Private Clinic — Moscow, Russian Federation (Recruiting)

Study contacts

• Study coordinator: Kirill Lobastov, PhD

Conditions Chronic Venous Disorder; Varicose Veins Leg; varicose veins; chronic venous disease; sclerotherapy; medical compression stockings