Program to improve heart health in patients with high blood pressure and cholesterol
Official title: Reducing Atherosclerotic Cardiovascular Disease (ASCVD) Through a Comprehensive Heart Disease Prevention Program (HDPP)
Run by University of Pennsylvania · NCT06062394 · Data updated 2026-11-12
This study is testing a six-month program to help people with high blood pressure and cholesterol improve their heart health using new support tools and strategies.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 35 Years to 80 Years |
| Sex | All |
| Enrollment | 1980 (estimated) |
| Sponsor | University of Pennsylvania Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Status | Recruiting |
| Started | March 11, 2024 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT06062394 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients registered with Penn Medicine who have elevated blood pressure and cholesterol levels and meet specific cardiovascular risk criteria.
✕Probably not a fit
Patients with certain exclusions such as those on specific cholesterol medications, those with severe health conditions, or non-English speakers may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This program aims to enroll patients from the Penn Medicine primary care network to participate in a six-month initiative focused on reducing hypertension and hyperlipidemia. Utilizing behavioral economics insights, the program encourages adherence to evidence-based interventions while relieving the burden on primary care providers through automated technology and a centralized support team. The effectiveness of the program will be evaluated by measuring changes in blood pressure and cholesterol levels over the six-month period for patients in West/Southwest Philadelphia and Lancaster, PA.
Why it matters
Potential benefit: If successful, this program could significantly improve heart health outcomes for patients with hypertension and high cholesterol.
How similar studies have gone: Other studies utilizing behavioral economics in health interventions have shown promising results, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * On the Penn Medicine Primary Care Service Line registry * Last 2 Blood Pressure readings with Systolic Blood Pressure \>=140 from any outpatient encounter in the last 12 months AND * ASCVD dx OR ASCVD risk score ≥10% OR Diabetes dx OR A1c ≥6.5 in last year OR Diabetes registry OR Last LDL ≥190 in past five years AND * Not on a statinor PCSK9, Inclisiran OR on a Low-intensity/moderate-intensity statin) with LDL \>100 Exclusion Criteria: * Patients on PCSK9 inhibitors * Documented statin allergy/ or intolerance in the EMR * Pregnancy * Breast feeding * Markedly shortened life expectancy including: 1. metastatic cancer 2. hospice 3. End Stage Renal Disease 4. Congestive Heart Failure 5. Dementia * Is a non-English speaker requiring a translator * Patients who do not have a cell phone
Where it's running
-
Penn Medicine
Philadelphia, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Kevin Volpp, MD, PhD — University of Pennsylvania
- Study coordinator: Kayla Clark, MPH
- Email: kayla.clark@pennmedicine.upenn.edu
- Phone: 215-746-4428
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.