Program to help Veterans transition to cardiac rehabilitation

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Not applicable Interventional VA Office of Research and Development · NCT06244199

This study tests a new program designed to help Veterans with heart issues join and stick with home-based rehabilitation to see if it improves their health and daily living.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorVA Office of Research and Development Federal
Locations2 sites (Boston, Massachusetts and 1 other locations)
Trial IDNCT06244199 on ClinicalTrials.gov

What this trial studies

This intervention focuses on improving participation in cardiac rehabilitation (CR) for Veterans with cardiovascular disease (CVD) who face barriers due to comorbidity and frailty. The Transition to CR (T2CR) program includes a two-day face-to-face assessment and planning phase that addresses individual risks and limitations, aiming to enhance the feasibility of home-based CR. Participants are randomized to receive either the T2CR intervention or usual care, with outcomes measured over one year in terms of functional capacity, participation in home-based CR, and overall health days at home.

Who should consider this trial

Good fit: Ideal candidates are male and female Veterans hospitalized with conditions such as ischemic heart disease, heart failure, or valvular heart disease who are willing to consider cardiac rehabilitation.

Not a fit: Patients with unstable medical conditions or end-stage diseases likely to be fatal within 12 months may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this program could significantly increase participation in cardiac rehabilitation among Veterans, leading to improved health outcomes and quality of life.

How similar studies have performed: Other studies have shown promise in improving cardiac rehabilitation participation through tailored interventions, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible candidates will consist of male and female Veterans hospitalized with:

  * ischemic heart disease (acute myocardial infarction or stable ischemia)
* revascularization (coronary artery bypass grafting or percutaneous coronary intervention)
* valvular heart disease (surgical or percutaneous intervention for mitral regurgitation or aortic stenosis)
* or heart failure (with reduced or preserved ejection fraction)
* All will be recruited while initially hospitalized and must express willingness to consider cardiac rehabilitation as a treatment option, including the possibility of the intervention which could possibly extend the length of their hospitalization (for 2 days maximum).
* Study candidates must also be English speaking and able to provide written informed consent

Exclusion Criteria:

* Veterans with unstable medical condition as indicated by history, physical exam, and/or laboratory findings end-stage disease likely to be fatal within 12 months
* severe cognitive impairment (MiniCog score 0-2)
* history of addictive or behavioral issues that confound safe administration of HBCR
* hearing loss that interferes with participation in the trial
* living in a long-term care living situation prior to the time of hospitalization, no plans to return to independent living after the hospitalization

Where this trial is running

Boston, Massachusetts and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiovascular DiseasesCardiac RehabilitationTransition of Carecardiovascular diseasescardiac rehabilitationtransition of care
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.