Program to help manage premenstrual disorders

Pilot Test of a Self-Directed Psychotherapy Program for Premenstrual Disorders

Not applicable Interventional University of Regina · NCT06648382

This study tests a self-help program to see if it can help people with premenstrual disorders feel better by tracking their symptoms over several menstrual cycles.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 42 Years
SexFemale
SponsorUniversity of Regina Academic / other
Locations2 sites (Regina, Saskatchewan and 1 other locations)
Trial IDNCT06648382 on ClinicalTrials.gov

What this trial studies

This study tests a self-help mental health program aimed at assisting individuals with premenstrual disorders, specifically premenstrual dysphoric disorder and premenstrual exacerbation of depression. Participants will track their daily symptoms for two menstrual cycles before starting the program, during the program, and for two additional cycles afterward. This approach allows researchers to compare symptom changes over time and assess the program's effectiveness in improving mental health outcomes.

Who should consider this trial

Good fit: Ideal candidates are women aged 18-42 who meet the diagnostic criteria for premenstrual dysphoric disorder or major depressive disorder with perimenstrual exacerbation.

Not a fit: Patients currently taking oral contraceptives or those engaged in psychotherapy may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could provide effective coping strategies for individuals suffering from premenstrual disorders, potentially improving their quality of life.

How similar studies have performed: While this approach is relatively novel, similar self-help programs for mental health have shown promise in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ages 18-42
* Either meeting diagnostic criteria for premenstrual dysphoric disorder (to be confirmed by researchers through daily symptom ratings for two menstrual cycles) or major depressive disorder with perimenstrual exacerbation (i.e. at least a 30% increase in 4 symptoms in the perimenstrual phase)

Exclusion Criteria:

* Taking oral contraceptives
* Currently in psychotherapy

Where this trial is running

Regina, Saskatchewan and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Premenstrual DisorderPremenstrual Dysphoric DisorderPsychotherapyPremenstrual disorderPremenstrual dysphoric disorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.