Program to help employees with stress-related issues return to work

Vital@Work: a Personalized Reintegration Program for Employees with Stress-related Complaints

Not applicable Interventional Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06543732

This study is testing a new program designed to help employees with stress-related issues get back to work by providing personalized support, and it's comparing this approach to standard care to see which works better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment208 (estimated)
Ages18 Years to 68 Years
SexAll
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other
Locations4 sites (Amsterdam and 3 other locations)
Trial IDNCT06543732 on ClinicalTrials.gov

What this trial studies

The Vital@Work program aims to assist sick-listed employees suffering from stress-related complaints in their return to work through a personalized eHealth intervention. Participants in the intervention group receive tailored support based on a distress screener, and if necessary, a structured Participatory Approach involving the employee, their supervisor, and a neutral facilitator. This randomized controlled trial compares the effectiveness of this program against standard care to evaluate improvements in return-to-work rates and overall mental health outcomes. The study is conducted across various organizations to assess its applicability in different work environments.

Who should consider this trial

Good fit: Ideal candidates are sick-listed employees aged 18-68 who have been on leave for 2 to 12 weeks due to stress-related complaints.

Not a fit: Patients with severe psychiatric disorders or chronic conditions that impede their ability to return to work may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly enhance the speed and sustainability of return to work for employees dealing with stress-related issues.

How similar studies have performed: Other studies have shown promising results with similar eHealth interventions for mental health, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Sick-listed employees from participating organisations (Amsterdam UMC, GGZ inGeest, Rijksschoonmaakorganisatie \[RSO\], and Transavia)
* Aged 18-68
* Between 2 and 12 weeks on sick leave
* Suffering from stress-related complaints

Exclusion Criteria:

* Non-sick-listed employees
* Suffering from severe psychiatric disorders (e.g., suicidality, mania, psychosis, schizophrenia) or other chronic conditions (e.g., terminal illness) that could significantly affect the employee's mental health and, hence, prevent the return-to work process
* Being pregnant or less than three months after delivery
* Sick-listed for more than 12 weeks
* Inability to complete either the eHealth modules or questionnaires
* Presence of a legal conflict with the employer
* Not signing informed consent

Where this trial is running

Amsterdam and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Return to WorkMental HealthReturn to workStressAbsenteeism
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.