Profiling imaging factors in prostate cancer treatment outcomes
Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
This study is trying to see if special MRI scans can help doctors better understand and treat prostate cancer in men aged 18 and older.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT03354416 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather data on the radiological and clinical progression of prostate cancer by utilizing multiparametric MRI (mpMRI) to identify imaging-based prognostic markers. Participants, men aged 18 and older with diagnosed or suspected prostate cancer, will allow researchers to access their medical history and imaging results for analysis. The goal is to enhance diagnosis and treatment decisions through the development of a decision-support system that incorporates imaging and clinical data.
Who should consider this trial
Good fit: Ideal candidates include men aged 18 and older with a diagnosis of prostate cancer or those at increased risk due to family history or genetic factors.
Not a fit: Patients without prostate cancer or those who do not meet the eligibility criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy and treatment strategies for prostate cancer patients.
How similar studies have performed: Other studies utilizing imaging-based biomarkers in prostate cancer have shown promise, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: * Patients with an increased risk for prostate cancer (strong family history and/or germline mutation in DNA repair genes), or with a diagnosis of prostatic cancer or suspicious for prostatic cancer lesions. * Age greater than or equal to 18 years * Ability of subject to understand and the willingness to sign a written informed consent document. EXCLUSION CRITERIA: -none
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Ismail B Turkbey, M.D. — National Cancer Institute (NCI)
- Study coordinator: Yolanda L McKinney, R.N.
- Email: ymckinney@mail.nih.gov
- Phone: (240) 760-6095
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.