Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Profiling imaging factors in prostate cancer treatment outcomes

Official title: Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

Run by National Institutes of Health Clinical Center (CC) · NCT03354416 · Data updated 2026-11-12

This study is trying to see if special MRI scans can help doctors better understand and treat prostate cancer in men aged 18 and older.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment10000 (estimated)
SponsorNational Institutes of Health Clinical Center (CC)
NIH
Locations1 site (Bethesda, Maryland)
StatusRecruiting
StartedFebruary 26, 2018
Main results expectedDecember 31, 2030
Study endsDecember 31, 2033
Registry record updatedOctober 16, 2026
Trial IDNCT03354416 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include men aged 18 and older with a diagnosis of prostate cancer or those at increased risk due to family history or genetic factors.

Probably not a fit

Patients without prostate cancer or those who do not meet the eligibility criteria may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on the radiological and clinical progression of prostate cancer by utilizing multiparametric MRI (mpMRI) to identify imaging-based prognostic markers. Participants, men aged 18 and older with diagnosed or suspected prostate cancer, will allow researchers to access their medical history and imaging results for analysis. The goal is to enhance diagnosis and treatment decisions through the development of a decision-support system that incorporates imaging and clinical data.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic accuracy and treatment strategies for prostate cancer patients.

How similar studies have gone: Other studies utilizing imaging-based biomarkers in prostate cancer have shown promise, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:
* Patients with an increased risk for prostate cancer (strong family history and/or germline mutation in DNA repair genes), or with a diagnosis of prostatic cancer or suspicious for prostatic cancer lesions.
* Age greater than or equal to 18 years
* Ability of subject to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA:

-none

Where it's running

  • National Institutes of Health Clinical Center
    Bethesda, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Ismail B Turkbey, M.D. — National Cancer Institute (NCI)
  • Study coordinator: Yolanda L McKinney, R.N.
  • Email: ymckinney@mail.nih.gov
  • Phone: (240) 760-6095

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.