Probiotics vs Zn/CHX Mouthwash for Halitosis and Plaque in Fixed Orthodontic Patients
Official title: Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients
Run by University of Baghdad · NCT07693972 · Data updated 2026-11-12
Aimed at seeing if probiotic lozenges or a zinc-chlorhexidine mouthwash can reduce bad breath and plaque in people with braces.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Baghdad Academic / other |
| Locations | 1 site (Baghdad, Alkargh) |
| Status | Recruiting |
| Started | December 31, 2025 |
| Main results expected | August 30, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | July 9, 2026 |
| Trial ID | NCT07693972 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults in good general health with fixed orthodontic appliances who do not use medications or have conditions affecting saliva, breath, or oral bacteria, and who have no contraindications to probiotics or antimicrobial mouth rinses.
✕Probably not a fit
Individuals with conditions or medications that affect saliva or oral microbiota, or those allergic to the study products, may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two oral care approaches in fixed orthodontic patients: probiotic lozenges containing Lactobacillus brevis CD2 and a zinc-chlorhexidine mouthwash. Participants will be assessed for plaque accumulation and halitosis to determine which regimen more effectively improves oral health markers. The study will recruit adults in good health without conditions or medications known to affect salivary flow, halitosis, or oral microbiota. Results will inform whether these products can be recommended to patients with fixed orthodontic appliances to manage halitosis and plaque. Primary outcomes include changes in plaque scores and breath odor measures.
Why it matters
Potential benefit: If successful, patients may experience reduced bad breath and cleaner teeth around braces.
How similar studies have gone: Other studies have explored probiotics and antimicrobial mouthwashes for halitosis and plaque, with mixed but promising results in related populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. good medical health 2. no systematic disease 3. non consuming drugs known to influence salivary flow, halitosis, or oral microbiota Exclusion Criteria: 1. alcohol drinking 2. smokers, pregnant and lactating womens 3. allergy or intolerance to corticosteroid treatment, antibiotic, antimicrobial mouth rinses, oral spray or tongue scraper, anti-inflammatory drugs or probiotics.
Where it's running
-
College of Dentistry
Baghdad, Alkargh, Iraq Recruiting
Study contacts
- Study coordinator: Sara M Almshhadany, assistant professor
- Email: drsara.mshhdany@codental.uobaghdad.edu.iq
- Phone: 006947715860084
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.