Probiotics for treating constipation in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of ABKefir, a probiotic, in alleviating symptoms of functional constipation in adults. A total of 165 participants will be randomly assigned to receive either a placebo, a low dose, or a high dose of ABKefir for 8 weeks. The study includes assessments of defecation patterns, anthropometric measurements, and biological samples at the start, mid-point, and end of the trial. The goal is to determine if probiotics can improve bowel function in individuals suffering from functional constipation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* male or female
* aged 18-75 years old
* fulfill Rome IV criteria for functional constipation
* have not participated in similar research in the past three months

Exclusion Criteria:

* Personal or family history of colon cancer, celiac disease, and inflammatory bowel disease
* Irritable bowel syndrome diagnosed during colonoscopy
* Those who are pregnant recently (including men and women), or are pregnant or breastfeeding women.
* Taking antidepressants, anti-anxiety drugs and other psychotropic drugs.
* Long-term medication is required to improve constipation
* Those diagnosed with myocardial infarction, cerebral infarction, malignant tumor and/or other serious diseases are not suitable for participating in the study.
* Allergic symptoms to probiotics or any ingredients
* Having a history of serious mental illness
* Drug-related crimes or alcohol problems
* Have recently traveled to areas where parasitic diseases are prevalent.

Where it's running

• Chung Shan Medical University
  Taichung, South, Taiwan Recruiting

Study contacts

• Principal investigator: Hsin-Chi Pan, MS student — Chung Shan Medical University
• Study coordinator: Chin-Lin Hsu, Professor
• Email: clhsu@csmu.edu.tw
• Phone: 04-24730022

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Probiotic treatment for constipation in pregnant women

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.