Probiotic treatment for respiratory and gastrointestinal illnesses in young children

Effects of Probiotic Against Respiratory & Gastrointestinal Illnesses in Children

Not applicable Interventional Universiti Sains Malaysia · NCT05734417

This study is testing if a specific probiotic can help prevent respiratory and stomach illnesses in preschool children under 7 years old in Malaysia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages1 Month to 84 Months
SexAll
SponsorUniversiti Sains Malaysia Academic / other
Locations1 site (Kuantan, Pahang)
Trial IDNCT05734417 on ClinicalTrials.gov

What this trial studies

This project investigates the effects of the probiotic Bifidobacterium lactis subsp. infantis B8762 on respiratory and gastrointestinal illnesses in preschool children under 7 years old in Malaysia. The study aims to determine whether probiotics can effectively prevent these common infections, which currently lack effective treatments. The methodology includes administering the probiotic and a placebo to assess their impact on illness incidence and severity. The research is grounded in existing evidence that probiotics may enhance immune function and compete with pathogens.

Who should consider this trial

Good fit: Ideal candidates are preschool children under 7 years old who exhibit symptoms of respiratory and/or gastrointestinal diseases.

Not a fit: Patients on long-term medication for severe illnesses or those with G6PD deficiency may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a safe and effective method for reducing respiratory and gastrointestinal illnesses in children.

How similar studies have performed: Previous studies have shown promising results for probiotics in preventing respiratory and gastrointestinal infections, suggesting a potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* preschool children (\<7 years old), and having respiratory and/or gastrointestinal diseases symptoms.
* Willing to commit throughout the experiment

Exclusion Criteria:

* Long term medication due to certain severe illness (6 months or more)
* Glucose-6-phosphate dehydrogenase (G6PD) deficiency

Where this trial is running

Kuantan, Pahang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Respiratory Tract Infectionsprobioticrespiratory tract infectionsBifidobacteriumchildren
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.