Preventing urinary retention after thoracic surgery in older men
Official title: Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Run by Hackensack Meridian Health · NCT03609580 · Data updated 2026-11-12
This study tests if giving Tamsulosin before and after thoracic surgery can help older men avoid urinary retention and the need for catheters.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Ages | 50 Years and up |
| Sex | Men only |
| Enrollment | 127 (estimated) |
| Sponsor | Hackensack Meridian Health Academic / other |
| Locations | 1 site (Hackensack, New Jersey) |
| Status | Recruiting |
| Started | May 7, 2018 |
| Main results expected | March 30, 2027 |
| Study ends | March 30, 2027 |
| Registry record updated | June 11, 2026 |
| Trial ID | NCT03609580 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are males aged 50 and older who are scheduled for minimally invasive thoracic surgical procedures.
✕Probably not a fit
Patients who are already using Flomax, have certain medical conditions, or have undergone prostate surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to reduce the incidence of post-operative urinary retention (POUR) in older men undergoing thoracic surgery by administering Tamsulosin (Flomax) before and after the procedure. The medication is intended to relax the prostate and improve urinary flow, potentially preventing the need for uncomfortable catheterization. The study will involve male participants aged 50 and older who are scheduled for minimally invasive thoracic surgeries. The effectiveness of Tamsulosin will be evaluated by comparing the rates of urinary retention in those receiving the medication versus standard care.
Why it matters
Potential benefit: If successful, this approach could significantly reduce urinary retention complications, leading to improved patient comfort and shorter hospital stays.
How similar studies have gone: Other studies have indicated that pre-operative use of medications like Tamsulosin can be effective in reducing urinary retention, suggesting a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Males ≥50 years old Planned surgical procedure of a minimally invasive thoracic surgical procedure (wedge resection, segmentectomy, lobectomy, pleural biopsy, or pleurodesis) Surgery scheduled more than 3 days from the time of consent Exclusion Criteria: * Using Flomax already * Allergy to Flomax or sulfa drugs * Current use of alpha blockers or alpha agonists * Resting systolic blood pressure \<100 * Orthostatic hypotension of \>20mm Hg (millimeters of mercury) Systolic and/or 10mm Hg diastolic pressure from sitting to standing (after 2 minutes of standing) as measured at the time of consent * Known diagnosis of congestive heart failure and valvular heart disease * History of prostate surgery (prostatectomy, trans-urethral resection)
Where it's running
-
Michael Spallone
Hackensack, New Jersey, United States Recruiting
Study contacts
- Principal investigator: Michael Spallone, MD — Hackensack Meridian Health
- Study coordinator: Michael Spallone, MD
- Email: michael.spallone@hmhn.org
- Phone: 551-996-2000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.