Preventing postpartum depression in immigrant Latinas

Preventing Postpartum Depression Among Immigrant Latinas Though a Virtual Group Intervention

Not applicable Interventional Northwestern University · NCT05873569

This study is testing a virtual support group to see if it can help immigrant Latinas prevent postpartum depression by teaching them skills to manage their mood.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages16 Years and up
SexFemale
SponsorNorthwestern University Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT05873569 on ClinicalTrials.gov

What this trial studies

This project aims to prevent postpartum depression (PPD) among immigrant Latinas through a virtual group intervention called Mothers and Babies Virtual Group (MB-VG). The intervention is based on cognitive-behavioral therapy principles and is designed to teach mood regulation skills to women at risk for PPD. Given the unique challenges faced by immigrant Latinas, such as acculturative stress and limited access to traditional healthcare, this study seeks to deliver effective mental health support in a more accessible format. The effectiveness of this approach will be evaluated through a randomized controlled trial.

Who should consider this trial

Good fit: Ideal candidates for this study are Latina women who speak Spanish, are at least 16 years old, and are either pregnant or have a child under 9 months old with elevated depressive symptoms.

Not a fit: Patients who are experiencing moderate to severe depressive symptoms or who are not at risk for postpartum depression will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the incidence of postpartum depression among immigrant Latinas, improving their mental health and parenting outcomes.

How similar studies have performed: Other studies have shown success with similar virtual interventions for mental health, but this specific approach targeting immigrant Latinas is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-identify as Latina
* Speak Spanish
* Be at least 16 years old
* Be pregnant or have a child \<9 months
* Have access to a device they can use for MB-VG sessions.
* Elevated depressive symptoms either scores of 5-14 on the Edinburgh Postnatal Depression Scale (EPDS) and/or scores 3.5 or greater prenatally or 4.5 or greater prenatally on the Postpartum Depression Predictors Inventory.

Exclusion Criteria:

* Individuals who score \>14 on the EPDS are exhibiting moderately severe to severe depressive symptoms and will be excluded given our prevention focus.
* Individuals not at risk for PPD-i.e., EPDS scores \<5 and under the PDPI-R cutoff-will also be excluded.

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postpartum Depression
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.