Preventing postoperative delirium in older patients
Official title: Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (QV-POD-2)
Run by Charite University, Berlin, Germany · NCT04355195 · Data updated 2026-11-12
This study is trying to see if new care methods can help prevent confusion after surgery in older patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 70 Years and up |
| Sex | All |
| Enrollment | 18100 (estimated) |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 2 sites (Berlin and 1 other locations) |
| Status | Recruiting |
| Started | April 20, 2020 |
| Main results expected | June 2028 |
| Study ends | June 2029 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT04355195 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients aged 70 years and older who are undergoing elective or non-elective surgery and are insured with specific health insurance providers.
✕Probably not a fit
Patients who are moribund or lack sufficient language skills may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The QV-POD-2 project aims to enhance the care of older patients undergoing surgery by implementing evidence-based measures to prevent postoperative delirium. This observational study will document patient outcomes through an electronic patient file, allowing for early identification and treatment of delirium symptoms. The initiative is a continuation of a previous quality contract aimed at improving inpatient care and will run for five years. The study will measure the incidence of delirium and other quality indicators as defined by the Institute for Quality Assurance and Transparency in Health Care.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of postoperative delirium in older patients, improving their recovery and overall quality of life.
How similar studies have gone: Previous studies have shown success in implementing preventive measures for postoperative delirium, making this approach both relevant and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Age ≥ 70 years * male and female patients * Patients who are insured with BARMER, HEK, KKH, DAK, TK or hkk Health insurances * Patients eligible for inclusion: by the patient, preoperatively * Incapacitated patients for inclusion: Written informed consent by a legal representative * surgery (elective and not elective) Exclusion criteria: * Moribund patients * Not enough language skills
Where it's running
-
Department of Anesthesiology and Intensive Care Medicine (CBF), Charité - Universitätsmedizin Berlin
Berlin, Germany Recruiting -
Department of Anesthesiology and Intensive Care Medicine (CCM/CVK) Berlin, Carité - Universitätsmedizin Berlin
Berlin, Germany Recruiting
Study contacts
- Study coordinator: Claudia Spies, MD, Prof.
- Email: claudia.spies@charite.de
- Phone: +49 30 450 55 11 02
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Low-dose Esketamine for preventing delirium in elderly patients undergoing surgery
This study is testing if low-dose Esketamine can help prevent confusion after surgery in older adults aged 65 to 90.
-
Sleep, Cognition, and Pain Bundle versus ERAS‑cardiac to Prevent Delirium After Heart Surgery
This trial will try a package of sleep improvement, pre-surgery brain exercises on a tablet, and 48 hours of IV acetaminophen alongside standard ERAS care to see if it lowers delirium in people 60 and older having planned heart surgery.
-
Daily nurse screening for delirium in hospitalized older adults
This study is testing if daily screenings for delirium by nurses can help improve care and outcomes for older adults in hospitals.
-
Huperzine A Injection to reduce postoperative delirium in elderly patients after non-cardiac surgery
This study is testing if an injection of Huperzine A can help older patients, aged 75 and up, avoid confusion and delirium after non-heart surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.