Preventing pain after spinal surgery
PREventing Pain After Surgery: a Feasibility and Acceptability Study of Acceptance and Commitment Therapy for the Prevention of Chronic Post-surgical Pain (PREPS)
This study is testing a short therapy program before spinal surgery to see if it can help prevent long-lasting pain and reduce the need for opioids afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 140 (estimated) |
| Ages | 22 Years and up |
| Sex | All |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 1 site (Chestnut Hill, Massachusetts) |
| Trial ID | NCT05306665 on ClinicalTrials.gov |
What this trial studies
This study aims to adapt a brief presurgical Acceptance and Commitment Therapy (ACT) intervention to prevent chronic post-surgical pain and reduce long-term opioid use following lumbar spine surgery. The intervention's acceptability, feasibility, and preliminary efficacy will be assessed six months after surgery. Additionally, the study will explore psychosocial and psychophysical factors that may influence the effectiveness of the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults aged 22 and older scheduled for specific spinal surgeries such as fusion or discectomy.
Not a fit: Patients with cognitive impairments, previous spinal surgeries, or specific spinal conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of chronic pain and reliance on opioids after spinal surgery.
How similar studies have performed: While the use of Acceptance and Commitment Therapy is gaining traction, this specific adaptation for preventing chronic pain post-surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foraminotomy * age 22 and older * able to communicate fluently in English Exclusion Criteria: * inability to complete study procedures due to delirium, dementia, psychosis, or other cognitive impairment * have a history of severe neurologic movement disorder * are pregnant or intent to become pregnant during study * have undergone previous spinal surgery * have spinal deformity, pseudarthrosis, trauma, infection, or tumor as primary indication for surgery * have undergone Acceptance and Commitment Therapy in last 2 years
Where this trial is running
Chestnut Hill, Massachusetts
- Brigham and Women's Hospital — Chestnut Hill, Massachusetts, United States (Recruiting)
Study contacts
- Study coordinator: Samantha M Meints, PhD
- Email: smeints@bwh.harvard.edu
- Phone: 6177329014
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.