Preventing ovarian cancer during colorectal surgery
Official title: Preventing Ovarian Cancer Through the Expansion of Opportunistic Salpingectomy: Uptake, Safety and Cost-effectiveness at the Time of Colorectal Surgery
Run by University of British Columbia · NCT05300711 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if removing fallopian tubes during colorectal surgery can help prevent ovarian cancer for women having that surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 80 Years |
| Sex | Women only |
| Enrollment | 240 (estimated) |
| Sponsor | University of British Columbia Academic / other |
| Locations | 2 sites (Vancouver, British Columbia and 1 other locations) |
| Trial ID | NCT05300711 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women with intact fallopian tubes who are undergoing specific types of colorectal surgery and have completed childbearing.
✕Probably not a fit
Patients with BRCA 1 or 2 mutations will not benefit from this study as they are excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the feasibility, safety, and cost-effectiveness of opportunistic salpingectomy (OS), which involves the removal of fallopian tubes, performed concurrently with colorectal surgery to prevent ovarian cancer. The research will enroll 120 participants who will undergo OS and compare them to a control group of 120 participants who will have colorectal surgery without OS. The study aims to gather data on the consent rates for OS, the safety of the procedure, and the perspectives of patients who decline participation. The findings could inform future practices regarding ovarian cancer prevention during colorectal surgeries.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of ovarian cancer in women undergoing colorectal surgery.
How similar studies have gone: While opportunistic salpingectomy has been shown to be safe and effective during gynecologic surgeries, this specific application during colorectal surgery is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with intact fallopian tubes. * Individuals undergoing one of the following open or laparoscopic colorectal surgery: total colectomy, right hemicolectomy, left hemicolectomy, anterior resection, low anterior resection, small bowel resection and appendectomy. * Individuals who finished with childbearing. Exclusion Criteria: * Presence of BRCA 1 or 2 mutation.
Where it's running
-
St. Paul's Hospital
Vancouver, British Columbia, Canada Recruiting -
Vancouver General Hospital
Vancouver, British Columbia, Canada Not yet recruiting
Study contacts
- Principal investigator: Gillian Hanley, PhD — University of British Columbia
- Study coordinator: Gillian Hanley, PhD
- Email: Gillian.Hanley@vch.ca
- Phone: 778-888-5822
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pain management plan implementation for major open abdominal surgeries
This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.
-
Bowel Sounds and Day-to-Day Recovery After Colorectal Cancer Surgery
This study will test whether monitoring bowel sounds before and after colorectal cancer surgery can predict how quickly patients recover bowel function and resume eating.
-
Bilateral ESPB versus OSTAPB for postoperative pain after colorectal surgery
This study tests whether, after open colorectal surgery, an ultrasound-guided bilateral erector spinae plane block works better or the bilateral OSTAP block works better for controlling pain.
-
Preventing colon anastomotic leaks by stenting the superior mesenteric artery
This trial tests whether placing a stent in the superior mesenteric artery before elective colon surgery can reduce anastomotic leaks in patients over 40 with an asymptomatic >50% SMA stenosis.
-
Using fingertip CRP point-of-care tests to spot leaks after elective colorectal surgery
This project will see if daily fingertip CRP point-of-care tests can detect anastomotic leaks early in people having elective colorectal surgery.
-
Peripheral autonomic plus TAP blocks for pain after minimally invasive left-sided colorectal surgery
This will try adding a peripheral autonomic block (targeting the superior hypogastric and inferior mesenteric plexuses) plus a TAP block to standard pain control in adults having elective minimally invasive left-sided colorectal surgery to see if it reduces pain and opioid use in the first 48 hours.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.