Preventing lung complications after gynecologic surgery using high-flow nasal oxygen

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of high-flow nasal cannula (HFNC) oxygen therapy in preventing postoperative pulmonary complications in patients undergoing gynecologic surgery. Patients at high risk for these complications will be randomly assigned to receive either HFNC or conventional nasal cannula oxygen therapy. The primary outcome measured will be the incidence of postoperative pulmonary complications such as hypoxemia, atelectasis, and pneumonia, while secondary outcomes will include improvements in oxygenation, antibiotic use, length of hospital stay, and any adverse events related to the oxygen therapy. The study will enroll patients aged 18 to 90 with specific respiratory risk factors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with gynecologic Neoplasms, including benign gynecologic tumors and malignant gynecologic tumors, who are 18 to 90 years old and are scheduled for surgical treatment in our center shall receive plain chest CT scan within 1 week before surgery, and the estimated surgical time shall be ≥2 hours, and at least one of the following conditions shall be met:

  1. Assess respiratory risk in surgical patients in Catalonia (ARRSPC) ≥45 points;
  2. BMI≥30;
  3. Moderate to severe asthma;
  4. Moderate to severe chronic obstructive pulmonary disease (COPD);
  5. Smoking history ≥20 packs/year

Exclusion Criteria:

1. Patients with lung metastasis of malignant tumor or primary lung malignant tumor;
2. previous lung surgery or radiotherapy;
3. the surgery involved segmental bowel resection.

Where it's running

• Sichuan Cancer Hospital and Research Institute
  Chengdu, Sichuan, China Recruiting

Study contacts

• Principal investigator: Dengfeng Wang, M.D. — Sichuan Cancer Hospital and Research Institute
• Study coordinator: Dengfeng Wang, M.D.
• Email: wonderful_96@163.com
• Phone: +86 159 82222707

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.