Preventing infections in hemodialysis patients during catheter placement with antibiotics

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of prophylactic antibiotics in reducing early catheter-related infections among hemodialysis patients at high risk. Participants will be randomized into two groups: one receiving antibiotics such as cefamezine and gentamicin, and the other receiving no antibiotics before catheter placement. The study will assess the incidence of infections and secondary complications within 45 days of catheter insertion. The goal is to determine if antibiotic administration can significantly lower infection rates and associated morbidity and mortality.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hemodialysis patients scheduled for new tunneled catheter placement or replacement of an existing tunneled catheter.
* Prior diagnosis of at least one of the following conditions:

  1. Atrial fibrillation
  2. Heart failure
  3. Femoral tunneled catheter

     * Patients who have signed informed consent to participate in the study.

Exclusion Criteria:

* • Hemodialysis patients unable to provide informed consent and requiring a legal guardian.

  * Patients undergoing prolonged antibiotic therapy prior to tunneled catheter insertion.

Where it's running

• Galilee Medical Center
  Nahariya, Israel, Israel Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.