Preventing frailty in people living with HIV aged 65–74
Official title: A Pilot Project for PLWH Aged 65-75: Preventing the Development of Frailty
Run by Centre Hospitalier Universitaire Saint Pierre · NCT07486661 · Data updated 2026-11-12
This project will see if using the Fried frailty screen and offering a linked care pathway can identify and help prevent frailty in people living with HIV aged 65–74.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years to 74 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Centre Hospitalier Universitaire Saint Pierre Academic / other |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | August 28, 2025 |
| Main results expected | July 2028 |
| Study ends | July 2028 |
| Registry record updated | March 20, 2026 |
| Trial ID | NCT07486661 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People living with HIV aged 65–74 who can attend visits at CHU Saint-Pierre or centre MIA in Brussels and can provide informed consent are ideal candidates.
✕Probably not a fit
People younger than 65 or older than 74, those without HIV, those already severely frail beyond preventive interventions, or those unable to attend the Brussels sites are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational pilot in Brussels will screen people living with HIV aged 65–74 using the Fried frailty phenotype to determine how many meet criteria for frailty or pre-frailty. Researchers will characterize clinical and social features of participants who screen positive and compare Fried scale results with local clinical judgment to explore validity in this population. The project will also offer a model care pathway for those identified at risk, linking geriatric assessment and management services that are not routinely reimbursed for this age group. No experimental treatments are given; data collection will occur at CHU Saint-Pierre and the centre MIA and results will inform larger preventive programs.
Why it matters
Potential benefit: If successful, the project could enable earlier identification and a practical care pathway to prevent or delay frailty, reducing hospitalizations and preserving independence for older people living with HIV.
How similar studies have gone: The Fried frailty phenotype is widely used and has been applied in older and some HIV-positive cohorts, but targeted validation and prevention pathway work specifically for PLWH aged 65–74 is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * living with HIV * between 65-74 years Exclusion Criteria: * none
Where it's running
-
CHU Saint-Pierre, centre MIA
Brussels, Belgium Recruiting
Study contacts
- Study coordinator: Agnes LIBOIS, MD
- Email: maladiesinfectieuses@stpierre-bru.be
- Phone: +3225354130
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.