Preventing aspiration pneumonia in stroke patients with bulbar palsy
Comparison Between Incidence of Pneumonia in Non-ventilated Cerebrovascular Stroke Patients Suffering from Bulbar Palsy Depending on Nasogastric Tube Feeding and Those Who Are Totally Parenterally Fed.
This study is testing whether giving nutrition through an IV can help stroke patients with swallowing problems avoid aspiration pneumonia better than feeding them through a tube in their nose.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06395740 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of total parenteral nutrition (TPN) versus enteral feeding via nasogastric tube in preventing aspiration pneumonia in cerebrovascular stroke patients suffering from bulbar palsy. The study aims to determine whether TPN can provide better nutritional support and reduce the risk of aspiration pneumonia compared to traditional enteral feeding methods. Patients will be monitored for recovery and nutritional status over a specified period, focusing on the first week post-stroke when the risk of malnutrition is highest. The trial seeks to provide evidence-based recommendations for managing feeding in this vulnerable patient population.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who have experienced a cerebrovascular stroke within the first 7 days and are suffering from bulbar palsy.
Not a fit: Patients who are mechanically ventilated, have pre-existing pneumonia, or suffer from severe neurological or hemodynamic instability may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved nutritional management and reduced incidence of aspiration pneumonia in stroke patients with bulbar palsy.
How similar studies have performed: Previous studies have indicated that early enteral feeding may not be superior to TPN, suggesting that this approach is both relevant and necessary to explore further.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. cerebrovascular stroke patients either ischemic or haemorrhagic within first 7 days 2. Age above 18 years 3. patients suffering from bulbar palsy. Exclusion Criteria: - Mechanically ventilated patients at first presentation. 2. Patients suffering from attacks of fits. 3. Patients suffering from signs and symptoms of pneumonia before attack of cerebrovascular stroke. 4. Patients suffering from degenerative neurological diseases. 5. Patients with developmental delay or neurological disease. 6. Patients with hepatic or renal coma. 7. Patients with hemodynamic instability.
Where this trial is running
Cairo
- Abdallah Mahmoud Zaki Soudi — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Adel ELansary — Faculty of medicine, Ain Shams university
- Study coordinator: Abdallah soudi
- Email: dr.soudi2014@med.asu.edu.eg
- Phone: 01111228925
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.