Preserving the submandibular gland during neck dissection for oral cancer patients
Submandibular Gland Preservation During Neck Dissection for Oral Squamous Cell Carcinoma
This study tests if keeping the submandibular gland during surgery helps early-stage oral cancer patients live longer compared to those who have it removed.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | N/A to 90 Years |
| Sex | All |
| Sponsor | Peking University Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT03385720 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of preserving the submandibular gland during neck dissection in patients with early-stage oral squamous cell carcinoma. Participants are randomly assigned to either an experimental group, where the gland is preserved, or a control group, where it is removed. The study aims to compare survival and mortality rates between the two groups to assess the benefits of gland preservation. The trial focuses on patients with primary oral cancer, specifically those classified as T1N0 and T2N0.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with early-stage oral squamous cell carcinoma (T1N0 and T2N0).
Not a fit: Patients with cancer of the floor of the mouth will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve patient outcomes by reducing complications associated with gland removal.
How similar studies have performed: While there may be studies on neck dissection techniques, this specific approach to gland preservation is relatively novel and has not been widely tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Primary oral squamous cell carcinoma of early stage (T1N0 and T2N0). Exclusion Criteria: Cancer of the floor of the mouth.
Where this trial is running
Beijing, Beijing Municipality
- Peking University School of Stomatology — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Jia-Zeng Su, Dr.
- Email: sujiazeng@163.com
- Phone: 86 10 82195992
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.