Preserving jawbone after tooth extraction using a patient's own dentin
Comparative Effectiveness of Autologous Dentin Matrix for Al-veolar Ridge Preservation
This study is testing if using a patient's own tooth material can help keep their jawbone strong after having a tooth pulled.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Moscow State University of Medicine and Dentistry Academic / other |
| Locations | 1 site (Moscow) |
| Trial ID | NCT06541236 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of different bone grafting materials in preserving the alveolar ridge after tooth extraction. It involves a randomized clinical intervention where 80 patients needing tooth extractions are divided into four groups, each receiving a different type of grafting material, including autologous dentin matrix. The study aims to assess the quality of newly formed bone tissue in the extraction sites over a specified period. The research adheres to ethical guidelines and is conducted at the University Clinic of A. I. Evdokimov Moscow State University.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-70 requiring tooth extraction due to conditions like periapical periodontitis or chronic periodontitis.
Not a fit: Patients under 18, pregnant women, or those with severe comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the success of dental implants by improving bone quality in extraction sites.
How similar studies have performed: Previous studies have shown promise in using various grafting materials for alveolar ridge preservation, but the use of autologous dentin matrix is a relatively novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: To be included in the study, the treatment plan was discussed with each patient before surgery and an informed release form approved by the ethics committee was signed. Moreover, they met the following criteria: 1) Age from 18-70 years, 2) The presence of indications for tooth extraction: periapical periodontitis, fracture of the root or crown of the tooth without the possibility of rehabilitation, chronic periodontitis, 3) satisfactory oral hygiene. Exclusion Criteria: Patients under 18 years of age, pregnant women, and patients with severe comor-bidity in the stage of decompensation were not included in the study.
Where this trial is running
Moscow
- Moscow State Univerciry of medicine and dentistry — Moscow, Russia (Recruiting)
Study contacts
- Study coordinator: Nikolai Redko, PhD
- Email: dr.redko@mail.ru
- Phone: +79169544444
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.