Preoperative hydration for same-day discharge after joint surgery

Preoperative Oral Hydration in the Ambulatory Arthroplasty Population :A Single-Blinded Randomized Control Trial

NA · Hospital for Special Surgery, New York · NCT05520593

This study tests if drinking a special carbohydrate drink before joint surgery can help patients go home the same day by improving their recovery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment312 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorHospital for Special Surgery, New York (other)
Locations1 site (New York, New York)
Trial IDNCT05520593 on ClinicalTrials.gov

What this trial studies

This study investigates whether consuming a complex carbohydrate drink before surgery can reduce the length of hospital stay and improve same-day discharge rates for patients undergoing total joint arthroplasty. It aims to address the challenges of postoperative nausea, vomiting, and dizziness by optimizing preoperative hydration. The study focuses on patients scheduled for ambulatory total knee and hip arthroplasties, assessing the impact of hydration on their recovery outcomes.

Who should consider this trial

Good fit: Ideal candidates include those scheduled for ambulatory total knee or hip arthroplasties who agree to same-day discharge.

Not a fit: Patients with certain medical conditions, such as diabetes or chronic kidney disease, or those with a BMI outside the specified range may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to shorter hospital stays and improved recovery experiences for patients undergoing joint surgeries.

How similar studies have performed: While the specific approach of using a carbohydrate drink preoperatively is novel, similar studies on hydration and recovery have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Candidates for ambulatory total knee arthroplasty
* Candidates for ambulatory total hip arthroplasty
* Candidates for ambulatory revision knee arthroplasty (liner exchange only)
* Candidates for ambulatory revision hip arthroplasty (liner exchange only)
* Case scheduled before noon (12 pm)
* Patient agrees to same-day discharge and has a responsible adult to spend the night on the day of discharge

Exclusion Criteria:

* BMI less than 18.5 or greater than 37.0
* Patients with diabetes, chronic kidney disease, clotting disorders, or neurological conditions preventing control of the affected limb.
* Pregnant women
* Patients scheduled as ambulatory due to insurance mandates
* Patients with a history of active ischemia, significant valvular disease, significant arrhythmias, obstructive sleep apnea as per Hospital for Special Surgery guidelines, chronic opioid dependence (chronic daily opioid use for six or more months), and glomerular filtration rate \< 60ml/min.

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Same-day Discharge, Length of Stay, Carbohydrate Drink, Perioperative Fluids, Total Joint Arthroplasty, Nausea, Vomiting, Same-day total hip arthroplasty

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.