Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Preoperative hydration for same-day discharge after joint surgery

Official title: Preoperative Oral Hydration in the Ambulatory Arthroplasty Population :A Single-Blinded Randomized Control Trial

Run by Hospital for Special Surgery, New York · NCT05520593 · Data updated 2026-11-12

This study tests if drinking a special carbohydrate drink before joint surgery can help patients go home the same day by improving their recovery.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment312 (estimated)
SponsorHospital for Special Surgery, New York
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedNovember 7, 2022
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedApril 13, 2026
Trial IDNCT05520593 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include those scheduled for ambulatory total knee or hip arthroplasties who agree to same-day discharge.

Probably not a fit

Patients with certain medical conditions, such as diabetes or chronic kidney disease, or those with a BMI outside the specified range may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether consuming a complex carbohydrate drink before surgery can reduce the length of hospital stay and improve same-day discharge rates for patients undergoing total joint arthroplasty. It aims to address the challenges of postoperative nausea, vomiting, and dizziness by optimizing preoperative hydration. The study focuses on patients scheduled for ambulatory total knee and hip arthroplasties, assessing the impact of hydration on their recovery outcomes.

Why it matters

Potential benefit: If successful, this approach could lead to shorter hospital stays and improved recovery experiences for patients undergoing joint surgeries.

How similar studies have gone: While the specific approach of using a carbohydrate drink preoperatively is novel, similar studies on hydration and recovery have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Candidates for ambulatory total knee arthroplasty
* Candidates for ambulatory total hip arthroplasty
* Candidates for ambulatory revision knee arthroplasty (liner exchange only)
* Candidates for ambulatory revision hip arthroplasty (liner exchange only)
* Case scheduled before noon (12 pm)
* Patient agrees to same-day discharge and has a responsible adult to spend the night on the day of discharge

Exclusion Criteria:

* BMI less than 18.5 or greater than 37.0
* Patients with diabetes, chronic kidney disease, clotting disorders, or neurological conditions preventing control of the affected limb.
* Pregnant women
* Patients scheduled as ambulatory due to insurance mandates
* Patients with a history of active ischemia, significant valvular disease, significant arrhythmias, obstructive sleep apnea as per Hospital for Special Surgery guidelines, chronic opioid dependence (chronic daily opioid use for six or more months), and glomerular filtration rate \< 60ml/min.

Where it's running

  • Hospital for Special Surgery
    New York, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Jose A Rodriguez, MD — Hospital for Special Surgery, New York
  • Study coordinator: Jose Rodriguez, MD
  • Email: rodriguezjose@hss.edu
  • Phone: 212-552-5829

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.