Preoperative carbohydrate loading to improve recovery after bladder surgery
Impact of the Preoperative Carbohydrate Loading for Enhancing Recovery After Radical Cystectomy: a Randomized Controlled Trial.
NA · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla · NCT05913245
This study is testing if drinking carbohydrate drinks before bladder surgery can help patients recover faster compared to not eating anything at all.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (other) |
| Locations | 1 site (Seville) |
| Trial ID | NCT05913245 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of preoperative carbohydrate loading with maltodextrin beverages compared to strict fasting and water intake on recovery after radical cystectomy. The study aims to determine if carbohydrate loading can reduce the time it takes for intestinal function to return post-surgery, potentially improving patient outcomes. By challenging traditional fasting practices, the trial aligns with Enhanced Recovery After Surgery (ERAS) guidelines, which emphasize minimizing complications like paralytic ileus. Participants will be monitored for their recovery progress following the intervention.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are scheduled for elective radical cystectomy.
Not a fit: Patients with severe comorbidities such as renal or liver failure, or those with gastrointestinal issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery times and improved postoperative outcomes for patients undergoing radical cystectomy.
How similar studies have performed: Other studies have shown promising results with similar preoperative carbohydrate loading approaches, suggesting potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Written informed consent. * Patients older than 18 years old proposed for radical cystectomy. Exclusion Criteria: * American Society of Anesthesiologists (ASA) classification grade: IV * Renal failure (creatinine levels above 3 mg/dL or dialysis) * Liver failure (Child-Pugh B or higher) * Gastroesophageal reflux disease. * Gastrointestinal obstruction. * Ongoing treatment with corticosteroids. * Previous infections within the last 3 months.
Where this trial is running
Seville
- Fundación Pública Andaluza para la Gestión de Investigación de Salud en Sevilla — Seville, Spain (RECRUITING)
Study contacts
- Study coordinator: Daniel López-Herrera Rodríguez, PhD
- Email: dalohero@gmail.com
- Phone: 0034-955012276
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Anesthesia, Urologic Cancer, Surgery, cystectomy, fasting, preoperative carbohydrate treatment