Premedication options for claustrophobic patients undergoing MRI scans
Official title: Clonidine and Lorazepam Premedication for Claustrophobic Patients During MRI Scan
Run by Salem Anaesthesia Pain Clinic · NCT05876117 · Data updated 2026-11-12
This study tests whether different medications can help people with claustrophobia feel less anxious during MRI scans.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 99 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Salem Anaesthesia Pain Clinic Academic / other |
| Locations | 1 site (Surrey, British Columbia) |
| Status | Recruiting |
| Started | July 4, 2020 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | January 27, 2025 |
| Trial ID | NCT05876117 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients diagnosed with claustrophobia who have previously experienced incomplete MRI scans due to their condition.
✕Probably not a fit
Patients with cognitive disorders, major neuropsychiatric disorders, or those who cannot provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effectiveness of different premedication strategies for patients with claustrophobia undergoing MRI scans. Participants will receive either Lorazepam, Clonidine, or a combination of both at alternate MRI sessions. The severity of claustrophobia will be assessed using validated questionnaires before and after each scan. The goal is to determine if premedication can alleviate anxiety and improve the MRI experience for these patients.
Why it matters
Potential benefit: If successful, this study could help reduce anxiety and improve the MRI experience for claustrophobic patients.
How similar studies have gone: While studies on anxiety management during MRI scans exist, this specific approach using a crossover design with these medications is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosed with claustrophobia * previous incomplete MRI because of claustrophobia * adult patients * good treatment compliance * reliable Claustrophobia Questionnaire (CLQ) diary * reliable General Anxiety Disorder Questionnaire (GAD) diary * informed consent for diary review * consent for clinical record quality assurance review Exclusion Criteria: * poor treatment compliance * cognitive disorder * inability to provide consent * major neuropsychiatric disorder * unreliable diary * cannabis use * excessive alcohol intake * previous adverse/allergic reactions to clonidine * previous adverse/allergic reactions to lorazepam
Where it's running
-
Salem Anaesthesia Pain Clinic
Surrey, British Columbia, Canada Recruiting
Study contacts
- Principal investigator: Olu Bamgbade, MD,FRCPC — Salem Anaesthesia Pain Clinic
- Study coordinator: Olu Bamgbade, MD,FRCPC
- Email: salem.painclinic@gmail.com
- Phone: 17786286600
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.