Clinical trial Recruiting at 1 site Observational Ages 20 to 99

Premedication options for claustrophobic patients undergoing MRI scans

Official title: Clonidine and Lorazepam Premedication for Claustrophobic Patients During MRI Scan

Run by Salem Anaesthesia Pain Clinic · NCT05876117 · Data updated 2026-11-12

This study tests whether different medications can help people with claustrophobia feel less anxious during MRI scans.

Quick facts

Study typeObservational
Ages20 Years to 99 Years
SexAll
Enrollment50 (estimated)
SponsorSalem Anaesthesia Pain Clinic
Academic / other
Locations1 site (Surrey, British Columbia)
StatusRecruiting
StartedJuly 4, 2020
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedJanuary 27, 2025
Trial IDNCT05876117 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients diagnosed with claustrophobia who have previously experienced incomplete MRI scans due to their condition.

Probably not a fit

Patients with cognitive disorders, major neuropsychiatric disorders, or those who cannot provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effectiveness of different premedication strategies for patients with claustrophobia undergoing MRI scans. Participants will receive either Lorazepam, Clonidine, or a combination of both at alternate MRI sessions. The severity of claustrophobia will be assessed using validated questionnaires before and after each scan. The goal is to determine if premedication can alleviate anxiety and improve the MRI experience for these patients.

Why it matters

Potential benefit: If successful, this study could help reduce anxiety and improve the MRI experience for claustrophobic patients.

How similar studies have gone: While studies on anxiety management during MRI scans exist, this specific approach using a crossover design with these medications is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosed with claustrophobia
* previous incomplete MRI because of claustrophobia
* adult patients
* good treatment compliance
* reliable Claustrophobia Questionnaire (CLQ) diary
* reliable General Anxiety Disorder Questionnaire (GAD) diary
* informed consent for diary review
* consent for clinical record quality assurance review

Exclusion Criteria:

* poor treatment compliance
* cognitive disorder
* inability to provide consent
* major neuropsychiatric disorder
* unreliable diary
* cannabis use
* excessive alcohol intake
* previous adverse/allergic reactions to clonidine
* previous adverse/allergic reactions to lorazepam

Where it's running

  • Salem Anaesthesia Pain Clinic
    Surrey, British Columbia, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.