Prehabilitation program for patients with advanced ovarian cancer
Prehabilitation for Advanced Ovarian Cancer Patients
This study is testing a prehabilitation program to see if it helps women with advanced ovarian cancer recover better after surgery when they receive support during their chemotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Mayo Clinic Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT05047926 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the impact of a prehabilitation program initiated during neoadjuvant chemotherapy on surgical recovery for patients with stage IIIC-IV ovarian, fallopian tube, or primary peritoneal cancer. The study involves three cohorts: one undergoing primary surgery, one receiving neoadjuvant chemotherapy with in-person support, and another with remote support. Participants will engage in physical activity, receive nutritional supplements, and complete surveys and health coaching to assess their recovery and quality of life. The trial aims to measure frailty, adherence, and functional trends over time.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older diagnosed with stage IIIC or IV epithelial ovarian, fallopian tube, or primary peritoneal cancer who are planning to undergo curative treatment.
Not a fit: Patients with severe cognitive impairment or those who are currently pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could enhance surgical recovery and improve quality of life for patients undergoing treatment for advanced ovarian cancer.
How similar studies have performed: Other studies have shown promising results with prehabilitation approaches in surgical recovery, suggesting potential success for this intervention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 years old * Diagnosed with epithelial ovarian, fallopian tube, or primary peritoneal cancer based on imaging and physician diagnosis * Suspected Stage IIIC or IV disease based on clinician staging and imaging * Curative intent treatment with platinum-based chemotherapy * Planned surgical intervention at some point during treatment course * Ability to read English * No diagnosed severe cognitive impairment * Ability to provide consent * Ability to utilize technology to watch online modules for the Resilient Living Program Exclusion Criteria: * Hemiplegia or paraplegia * Current pregnancy
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Amanika A. Kumar, MD — Mayo Clinic in Rochester
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.