Prehabilitation program for elderly patients undergoing major surgery

Perioperative Outcomes of a Prehabilitation Programme for Surgical Patients Undergoing Major Surgery: a Pilot Interventional

Observational Singapore General Hospital · NCT06620588

This study is testing a prehabilitation program to see if it helps frail elderly patients improve their strength and recover better after major surgery.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages65 Years to 100 Years
SexAll
SponsorSingapore General Hospital Academic / other
Locations1 site (Singapore, Singapore)
Trial IDNCT06620588 on ClinicalTrials.gov

What this trial studies

This pilot interventional study evaluates the impact of a prehabilitation program on physical function and clinical outcomes in frail elderly patients scheduled for major non-cardiac surgery. The program includes preoperative physiotherapy assessment, nutrition education, exercise instructions, and inspiratory muscle training for patients with a maximal inspiratory pressure (MIP) of less than 100 cmH2O. Primary outcomes focus on changes in physical function, measured by handgrip strength, while secondary outcomes include various functional tests and assessment of postoperative complications. The study aims to enhance recovery and reduce complications through structured preoperative preparation.

Who should consider this trial

Good fit: Ideal candidates are patients over 65 years old who are undergoing elective major non-cardiac surgery and have an Edmonton Frail Score of 6 or higher.

Not a fit: Patients unable to provide written informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve physical function and reduce postoperative complications in frail elderly patients.

How similar studies have performed: Other studies have shown success with prehabilitation programs in improving outcomes for frail elderly patients, indicating this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged over 65 years who are undergoing elective major non-cardiac surgery
* Edmonton Frail Score (EFS) of 6 or higher

Exclusion Criteria:

* Patients who are unable to provide written informed consent

Where this trial is running

Singapore, Singapore

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prehabilitationfrailelderly
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.