Prehabilitation for lung cancer patients before surgery
Official title: Effects of Multimodal Prehabilitation on Cardiorespiratory Fitness and Pulmonary Function During Neoadjuvant Therapy in Patients With Locally Advanced Lung Cancer
Run by Hospital Clinic of Barcelona · NCT05636969 · Data updated 2026-11-12
This study is testing whether a special exercise and health program can help lung cancer patients feel stronger and healthier before their surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Hospital Clinic of Barcelona Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy |
| Locations | 1 site (Barcelona, Barcelona) |
| Status | Recruiting |
| Started | June 10, 2023 |
| Main results expected | February 1, 2027 |
| Study ends | June 1, 2027 |
| Registry record updated | October 15, 2026 |
| Trial ID | NCT05636969 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients diagnosed with non-small cell lung cancer who are set to undergo neoadjuvant therapy before surgery.
✕Probably not a fit
Patients with non-resectable tumors or those unable to perform required physical tests will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of multimodal prehabilitation on patients with non-small cell lung cancer (NSCLC) who are undergoing neoadjuvant therapy prior to lung resection surgery. It aims to compare the impact of neoadjuvant therapy on cardiorespiratory fitness and lung function, while also assessing the feasibility and safety of the prehabilitation intervention. Secondary objectives include evaluating functional capacity, mood, and self-reported physical activity levels. The study will measure various outcomes to determine the effectiveness of prehabilitation in improving patient health before surgery.
Why it matters
Potential benefit: If successful, this approach could enhance lung function and overall fitness in patients, potentially reducing postoperative complications.
How similar studies have gone: Previous studies have shown promising results with prehabilitation in surgical patients, suggesting potential benefits in this context as well.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients with diagnosed non-small celll lung cancer (NSCLC) undergoing neoadjuvant therapy before lung resection surgery Exclusion Criteria: * Physical impairments that prevent patients to perform a CardioPulmonary Exercise Test * Non-resectable tumours * Patients who refuse either surgical resection or neoadjuvant therapy
Where it's running
-
Hospital Clinic de Barcelona
Barcelona, Barcelona, Spain Recruiting
Study contacts
- Study coordinator: Raquel Sebio, PhD
- Email: sebio@clinic.cat
- Phone: +34634787194
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.