Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Prehabilitation for lung cancer patients before surgery

Official title: Effects of Multimodal Prehabilitation on Cardiorespiratory Fitness and Pulmonary Function During Neoadjuvant Therapy in Patients With Locally Advanced Lung Cancer

Run by Hospital Clinic of Barcelona · NCT05636969 · Data updated 2026-11-12

This study is testing whether a special exercise and health program can help lung cancer patients feel stronger and healthier before their surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorHospital Clinic of Barcelona
Academic / other
Drugs / interventionschemotherapy, immunotherapy
Locations1 site (Barcelona, Barcelona)
StatusRecruiting
StartedJune 10, 2023
Main results expectedFebruary 1, 2027
Study endsJune 1, 2027
Registry record updatedOctober 15, 2026
Trial IDNCT05636969 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients diagnosed with non-small cell lung cancer who are set to undergo neoadjuvant therapy before surgery.

Probably not a fit

Patients with non-resectable tumors or those unable to perform required physical tests will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of multimodal prehabilitation on patients with non-small cell lung cancer (NSCLC) who are undergoing neoadjuvant therapy prior to lung resection surgery. It aims to compare the impact of neoadjuvant therapy on cardiorespiratory fitness and lung function, while also assessing the feasibility and safety of the prehabilitation intervention. Secondary objectives include evaluating functional capacity, mood, and self-reported physical activity levels. The study will measure various outcomes to determine the effectiveness of prehabilitation in improving patient health before surgery.

Why it matters

Potential benefit: If successful, this approach could enhance lung function and overall fitness in patients, potentially reducing postoperative complications.

How similar studies have gone: Previous studies have shown promising results with prehabilitation in surgical patients, suggesting potential benefits in this context as well.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients with diagnosed non-small celll lung cancer (NSCLC) undergoing neoadjuvant therapy before lung resection surgery

Exclusion Criteria:

* Physical impairments that prevent patients to perform a CardioPulmonary Exercise Test
* Non-resectable tumours
* Patients who refuse either surgical resection or neoadjuvant therapy

Where it's running

  • Hospital Clinic de Barcelona
    Barcelona, Barcelona, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.