Prehabilitation for lung cancer patients before surgery

Effects of Multimodal Prehabilitation on Cardiorespiratory Fitness and Pulmonary Function During Neoadjuvant Therapy in Patients with Locally Advanced Lung Cancer

Not applicable Interventional Hospital Clinic of Barcelona · NCT05636969

This study is testing whether a special exercise and health program can help lung cancer patients feel stronger and healthier before their surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Clinic of Barcelona Academic / other
Drugs / interventionschemotherapy, immunotherapy
Locations1 site (Barcelona, Barcelona)
Trial IDNCT05636969 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of multimodal prehabilitation on patients with non-small cell lung cancer (NSCLC) who are undergoing neoadjuvant therapy prior to lung resection surgery. It aims to compare the impact of neoadjuvant therapy on cardiorespiratory fitness and lung function, while also assessing the feasibility and safety of the prehabilitation intervention. Secondary objectives include evaluating functional capacity, mood, and self-reported physical activity levels. The study will measure various outcomes to determine the effectiveness of prehabilitation in improving patient health before surgery.

Who should consider this trial

Good fit: Ideal candidates are adult patients diagnosed with non-small cell lung cancer who are set to undergo neoadjuvant therapy before surgery.

Not a fit: Patients with non-resectable tumors or those unable to perform required physical tests will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance lung function and overall fitness in patients, potentially reducing postoperative complications.

How similar studies have performed: Previous studies have shown promising results with prehabilitation in surgical patients, suggesting potential benefits in this context as well.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients with diagnosed non-small celll lung cancer (NSCLC) undergoing neoadjuvant therapy before lung resection surgery

Exclusion Criteria:

* Physical impairments that prevent patients to perform a CardioPulmonary Exercise Test
* Non-resectable tumours
* Patients who refuse either surgical resection or neoadjuvant therapy

Where this trial is running

Barcelona, Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Non Small Cell Lung Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.