Prediction model for train-of-four monitoring in neurosurgery
Investigation for Development of Predictive Model for Train of Four (TOF)% for Neurophysiological Monitoring During Neuroanesthesia
This study tests a new way to monitor how patients respond to anesthesia during brain surgery to see if it can help improve their care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Kangbuk Samsung Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT05963256 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop a prediction model for determining the train-of-four (TOF) 50% response in patients undergoing neurosurgery. It utilizes a twitch electrode array to monitor neurophysiological responses during surgery. The study focuses on patients who are scheduled for intra-operative neurophysiological monitoring and assesses their responses to anesthesia. By analyzing these responses, the researchers hope to improve monitoring techniques and patient outcomes during neurosurgical procedures.
Who should consider this trial
Good fit: Ideal candidates for this study are patients undergoing neurosurgery who are classified as American Society of Anesthesiologists physical class I, II, or III.
Not a fit: Patients who are unable to monitor train-of-four responses or who decline to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of neuromuscular monitoring during neurosurgery, leading to better patient safety and outcomes.
How similar studies have performed: While there may be existing studies on neuromuscular monitoring, this specific prediction model approach is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patient undergoing neurosurgery * scheduled for intra-operative neurophysiological monitoring * American Society of Anesthesiologists physical class I, II, III Exclusion Criteria: * unable to monitor train-of-four * decline to participate in the study
Where this trial is running
Seoul
- Eunah Cho — Seoul, Korea, Republic of (Recruiting)
Study contacts
- Principal investigator: Eunah Cho, PhD — KangbukSamsung Hospital
- Study coordinator: Eunah Cho, PhD
- Email: mintflavored@naver.com
- Phone: 82-10-9480-0531
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.