Clinical trial No longer in our active list Observational Ages 18 to 80

Predicting stroke risk in patients with chronic intracranial arterial occlusion using advanced imaging techniques

Official title: Developing and Validating a Prediction Model for Bidirectional Stroke Risk in Chronic Intracranial Arterial Occlusion Based on Multimodal CT Radiomic Features of Key Brain Regions.

Run by Beijing Hospital · NCT06066593 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is trying to see if a new computer model can help predict stroke risk in patients with blocked brain arteries who don't have any symptoms.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment1000 (estimated)
SponsorBeijing Hospital
Government
Locations2 sites (Beijing, Beijing and 1 other locations)
Trial IDNCT06066593 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include asymptomatic patients aged 18 to 80 diagnosed with chronic intracranial arterial occlusion.

Probably not a fit

Patients with acute intracranial arterial occlusive disease or a history of ischemic or hemorrhagic stroke may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop a machine learning-based model to assess long-term stroke risk in asymptomatic patients with chronic intracranial arterial occlusion. It will utilize multimodal CT scans to create a deep learning segmentation model for key brain regions, including the basal ganglia and lobes of the brain. The study will involve training the model on retrospective data and validating it with prospective data to ensure accuracy in predicting both ischemic and hemorrhagic stroke risks. The research seeks to enhance the understanding of neuroimaging features related to stroke in this patient population.

Why it matters

Potential benefit: If successful, this study could provide a more accurate prediction of stroke risk, allowing for better patient management and preventive strategies.

How similar studies have gone: While the use of machine learning in neuroimaging is a growing field, this specific approach to predicting stroke risk in chronic intracranial arterial occlusion is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with chronic intracranial arterial occlusion.
* Asymptomatic or with a history of only transient ischemic attacks (TIAs).
* The age of the patient falls within the range of 18 to 80 years old.
* Willing to undergo both perfusion CT scans and magnetic resonance imaging (MRI).

Exclusion Criteria:

* Acute intracranial arterial occlusive disease.
* History of either ischemic or hemorrhagic stroke.
* Allergies to contrast agents or conditions such as claustrophobia that prevent completion of imaging data acquisition.

Where it's running

  • Beijing Tiantan Hospital
    Beijing, Beijing, China
    Recruiting
  • Beijing Hospital
    Beijing, Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.