Predicting stroke risk in patients with chronic intracranial arterial occlusion using advanced imaging techniques
Official title: Developing and Validating a Prediction Model for Bidirectional Stroke Risk in Chronic Intracranial Arterial Occlusion Based on Multimodal CT Radiomic Features of Key Brain Regions.
Run by Beijing Hospital · NCT06066593 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is trying to see if a new computer model can help predict stroke risk in patients with blocked brain arteries who don't have any symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Beijing Hospital Government |
| Locations | 2 sites (Beijing, Beijing and 1 other locations) |
| Trial ID | NCT06066593 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include asymptomatic patients aged 18 to 80 diagnosed with chronic intracranial arterial occlusion.
✕Probably not a fit
Patients with acute intracranial arterial occlusive disease or a history of ischemic or hemorrhagic stroke may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to develop a machine learning-based model to assess long-term stroke risk in asymptomatic patients with chronic intracranial arterial occlusion. It will utilize multimodal CT scans to create a deep learning segmentation model for key brain regions, including the basal ganglia and lobes of the brain. The study will involve training the model on retrospective data and validating it with prospective data to ensure accuracy in predicting both ischemic and hemorrhagic stroke risks. The research seeks to enhance the understanding of neuroimaging features related to stroke in this patient population.
Why it matters
Potential benefit: If successful, this study could provide a more accurate prediction of stroke risk, allowing for better patient management and preventive strategies.
How similar studies have gone: While the use of machine learning in neuroimaging is a growing field, this specific approach to predicting stroke risk in chronic intracranial arterial occlusion is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed with chronic intracranial arterial occlusion. * Asymptomatic or with a history of only transient ischemic attacks (TIAs). * The age of the patient falls within the range of 18 to 80 years old. * Willing to undergo both perfusion CT scans and magnetic resonance imaging (MRI). Exclusion Criteria: * Acute intracranial arterial occlusive disease. * History of either ischemic or hemorrhagic stroke. * Allergies to contrast agents or conditions such as claustrophobia that prevent completion of imaging data acquisition.
Where it's running
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Beijing Tiantan Hospital
Beijing, Beijing, China Recruiting -
Beijing Hospital
Beijing, Beijing, China Recruiting
Study contacts
- Study coordinator: Shaosen Zhang, Doctor
- Email: longyoubafang@hotmail.com
- Phone: 18611284839
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.