Predicting sperm retrieval success in men with non-obstructive azoospermia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify molecular and biochemical markers that can predict the success of sperm retrieval in men diagnosed with non-obstructive azoospermia. By analyzing testicular proteins and other indicators, the study seeks to improve the understanding of spermatogenesis and enhance the chances of successful sperm extraction. The research will involve semen analysis and may provide insights into the histological characteristics of the testis. The ultimate goal is to better inform treatment options for couples facing infertility due to this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men with Non-obstructive azoospermia

Exclusion Criteria:

1. Sex reversal syndrome.
2. Macro-deletion on the Y chromosome (To those accepting the chromosomal study)
3. AZF a, AZF b microdeletion (To those accepting the Y chromosome microdeletion analysis).
4. Obstructive azoospermia.
5. Undescended testis.
6. Hypogonadotrophic Hypogonadism
7. Testicular procedures and operations -

Where it's running

• Cairo University hospital, department of andrology
  Cairo, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.